Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …

Poor water solubility of many drugs has emerged as one of the major challenges in the
pharmaceutical world. Polymer-based amorphous solid dispersions have been considered …

Spray drying is a well-established manufacturing technique which can be used to formulate
amorphous solid dispersions (ASDs) which is an effective strategy to deliver poorly water …

Over 40% of active pharmaceutical ingredients (API) in development pipelines are poorly
water-soluble drugs which limit formulation approaches, clinical application and …

Spray drying is an efficient technology for solid dispersion manufacturing since it allows
extreme rapid solvent evaporation leading to fast transformation of an API-carrier solution to …

Poorly water-soluble drugs pose a significant challenge to developability due to poor oral
absorption leading to poor bioavailability. Several approaches exist that improve the oral …

Abstract Purpose Amorphous solid dispersions (ASDs) have been widely used in the
pharmaceutical industry for solubility enhancementof poorly water-soluble drugs. The …

Application of amorphous solid dispersions (ASDs) is considered one of the most promising
approaches to increase the dissolution rate and extent of bioavailability of poorly water …

Introduction: Amorphous solid dispersions are considered as one of the most powerful
strategies to formulate poorly soluble drugs. They are made up of an active pharmaceutical …

Amorphous drug delivery systems are increasingly utilized to enhance aqueous solubility
and oral bioavailability. However, they lack physical and/or chemical stability. One of the …