A model of microtubule depolymerization by kinesin-8 motor proteins.

P Xie - Advances in Protein Chemistry and Structural Biology, 2023 - europepmc.org
The dimeric kinesin-8 motors have the biological function of depolymerizing microtubules
(MTs) from the plus end. However, the molecular mechanism of the depolymerization …

Modeling study of kinesin-13 MCAK microtubule depolymerase

P Xie - European Biophysics Journal, 2024 - Springer
Mitotic centromere-associated kinesin (MCAK) motor protein is a typical member of the
kinesin-13 family, which can depolymerize microtubules from both plus and minus ends. A …

A model for the catalytic activity of microtubule polymerases

P Xie - Cytoskeleton, 2023 - Wiley Online Library
Abstract A XMAP215/Stu2/Alp14 polymerase can catalyze processively the tubulin addition
to the microtubule (MT) plus end. In this work, a model is proposed for the underlying …

A Quick and Reproducible Silanization Method by Using Plasma Activation for Hydrophobicity‐Based Kinesin Single Molecule Fluorescence–Microscopy Assays

V Wedler, D Quinones, H Peisert… - Chemistry–A European …, 2022 - Wiley Online Library
Single‐molecule assays often require functionalized surfaces. One approach for microtubule
assays renders surfaces hydrophobic and uses amphiphilic blocking agents. However, the …

Multi-camera Simultaneous Total Internal Reflection and Interference Reflection Microscopy

J Spector, J Chen, A Roll-Mecak - bioRxiv, 2024 - biorxiv.org
Interference Reflection Microscopy (IRM) is an optical technique that relies on the
interference between the reflected light from an incident beam as it passes through materials …

Methods for high-contrast photoluminescence and label-free surface-sensitive detection

V Wedler - 2023 - tobias-lib.ub.uni-tuebingen.de
Physical phenomena such as total internal reflection, scattering and interference, or
plasmon resonances enable surface-sensitive detection methods. These methods have high …

A Model for the Molecular Mechanism of Kinesin-8 Motors Depolymerizing Microtubules

P Xie - Available at SSRN 4269840 - papers.ssrn.com
The dimeric kinesin-8 motors have the biological function of depolymerizing microtubule
(MT) from the plus end by residing at the end for a long time. However, the molecular …