The heterogeneity in the healthy human immune system, and the immunological changes
that portend various diseases, have been only partially described. Their comprehensive …

Development of DNA biosensors and DNA microarrays has increased tremendously over
the past few years as demonstrated by the large number of scientific publications in this area …

Two types of stem cells are currently defined in small intestinal crypts: cycling crypt base
columnar (CBC) cells and quiescent '+ 4'cells. Here, we combine transcriptomics with …

We describe a technology, the NanoString nCounter gene expression system, which
captures and counts individual mRNA transcripts. Advantages over existing platforms …

Gene expression data from microarrays are being applied to predict preclinical and clinical
endpoints, but the reliability of these predictions has not been established. In the MAQC-II …

Motivation: Statistical methods are used to test for the differential expression of genes in
microarray experiments. The most widely used methods successfully test whether the true …

Over the last decade, the introduction of microarray technology has had a profound impact
on gene expression research. The publication of studies with dissimilar or altogether …

Lignin engineering is an attractive strategy to improve lignocellulosic biomass quality for
processing to biofuels and other bio-based products. However, lignin engineering also …

RNA sequencing is an increasingly popular technology for genome-wide analysis of
transcript sequence and abundance. However, understanding of the sources of technical …

Background Tumours rapidly ferment glucose to lactic acid even in the presence of oxygen,
and coupling high glycolysis with poor perfusion leads to extracellular acidification. We …