Patients with depression often suffer from sleep disorders and non-sleep circadian
disorders. However, whether they precede and predict subsequent depression is unclear …

Photoperiodism is the ability of plants and animals to measure environmental day length to
ascertain time of year. Central to the evolution of photoperiodism in animals is the adaptive …

Interactions among suprachiasmatic nucleus (SCN) neurons are required for robust
circadian rhythms entrained to local time. To investigate these signaling mechanisms, we …

Individuals are increasingly exposed to light at night. Exposure to constant light (LL) disrupts
circadian rhythms of locomotor activity, body temperature, hormones, and the sleep-wake …

Affective disorders such as major depression, bipolar disorder, and seasonal affective
disorder are associated with major disruptions in circadian rhythms. Indeed, altered …

Pregnancy and motherhood constitute periods of tremendous hormonal variation that
orchestrate parturition, lactation, maternal care, maternal aggression, and recognition of …

The serotonin and circadian systems are principal regulatory networks of the brain. Each
consists of a unique set of neurons that make widespread neural connections and a defined …

In depression, symptoms range from loss of motivation and energy to suicidal thoughts.
Moreover, in depression alterations might be also observed in the sleep-wake cycle and in …

Using real-time gene expression imaging and behavioral analysis, we found that the
perinatal photoperiod has lasting effects on the circadian rhythms expressed by clock …

Earlier findings show seasonality in processes and behaviors such as brain plasticity and
depression that in part are regulated by Brain-Derived Neurotrophic Factor (BDNF). Based …