Identification of phytoconstituents as potent inhibitors of casein kinase-1 alpha using virtual screening and molecular dynamics simulations

A Shafie, S Khan, Zehra, T Mohammad, F Anjum… - Pharmaceutics, 2021 - mdpi.com
Casein kinase-1 alpha (CK1α) is a multifunctional protein kinase that belongs to the
serine/threonine kinases of the CK1α family. It is involved in various signaling pathways …

Prenylated PALM2 promotes the migration of esophageal squamous cell carcinoma cells through activating ezrin

DX Deng, CY Li, ZY Zheng, B Wen, LD Liao… - Molecular & Cellular …, 2023 - ASBMB
Proteins containing a CAAX motif at the C-terminus undergo prenylation for localization and
activity and include a series of key regulatory proteins, such as RAS superfamily members …

[HTML][HTML] Casein kinase 1 controls the shuttling of epidermal growth factor receptor and estrogen receptor in endometrial carcinoma induced by breast cancer hormonal …

LN Hoang, SJ Lee - Cellular Signalling, 2023 - Elsevier
Casein kinase 1 plays a crucial role in carcinogenesis. 4-Hydroxytamoxifen (4-OHT), which
is widely used to treat breast cancer, often leads to the development of endometrial …

miR-181a 在卵巢癌细胞中对顺铂的耐药作用.

徐丽秀, 美力班, 吐尔逊, 克热曼… - Journal of Kunming …, 2022 - search.ebscohost.com
目的探讨miR-181a 在卵巢癌化疗抵抗方面的影响及其机制. 方法qRT-PCR
检测卵巢癌细胞A2780 及A2780/DDP 中miR-181a 的表达; 对A2780 及A2780/DDP …

Phosphorylation of the Autographa californica multiple nucleopolyhedrovirus polyhedron envelope protein plays an important role in the formation of the occlusion …

J Wang, J Yang, C Lei, X Sun… - Journal of General …, 2022 - microbiologyresearch.org
During the life cycle of a baculovirus, a crystallized protein matrix, formed by polyhedrin
(POLH), is produced. The protein matrix is surrounded by a multilayered …

Infection of human blood-brain barrier cells in vitro by different subtypes of enterovirus a71 and its consequences on permeability and particles release

IL Coqueiro - 2023 - theses.hal.science
The blood-brain barrier (BBB) formed by the brain microvasculature can be circumvented
during the invasion of the central nervous system (CNS) by neurotropic viruses. Enterovirus …

[PDF][PDF] Université Clermont Auvergne

IL Coqueiro - 2023 - scholar.archive.org
The blood-brain barrier (BBB) formed by the architecture of brain microvasculature may be
circumvented during the invasion of neurotropic viruses into the central nervous system …

[PDF][PDF] Évaluation des biomarqueurs de sévérité liés à la COVID-19

A Fatima-Zahra - 2022 - toubkal.imist.ma
Résumé L'infection par le nouveau coronavirus est caractérisée par un mécanisme d'action
qui déclenche de nombreux phénomènes pathogéniques aboutissant à plusieurs …

Studies on Cisplatin Resistance of miR-181a in Ovarian Cancer Cells

XU Lixiu, T Meiliban, Y Kereman - 昆明医科大学学报, 2022 - kyxuebao.kmmu.edu.cn
Objective To investigate the effect of miR-181a on chemotherapy resistance of ovarian
cancer and its regulatory mechanism. Methods Real-time PCR was used to detect the …