Exposure to dust from the mining environment has historically resulted in epidemic levels of
mortality and morbidity from pneumoconiotic diseases such as silicosis, coal workers' …

This review provides an overview of literature addressing progressive massive fibrosis
(PMF) from September 2009 to the present. Advances are described in understanding its …

Interstitial lung diseases (ILDs) are a heterogeneous group of parenchymal lung diseases,
some of which arise as a result of genetic susceptibility, as well as external noxious stimuli …

An ongoing resurgence of occupational lung disease among coal miners in the United
States has been linked to respirable crystalline silica (RCS). To better protect miners, a …

Respirable crystalline silica is now considered to be a major culprit of resurgent lung
disease among US coal miners—especially in central Appalachia—though questions …

Abstract Direct-on-Filter (DoF) analysis of respirable crystalline silica (RCS) by Fourier
Transform Infrared (FTIR) spectroscopy is a useful tool for assessing exposure risks. With the …

The pathophysiology of silicosis is poorly understood, limiting development of therapies for
those who have been exposed to the respirable particle. We explored mechanisms of silica …

Context.—The pathology of coal workers' pneumoconiosis (CWP) and its most severe form—
progressive massive fibrosis (PMF)—in US coal miners has changed in recent years. Severe …

Context.—Overexposure to respirable coal mine dust can cause severe lung disease
including progressive massive fibrosis (PMF). Field emission scanning electron microscopy …

Pneumoconioses represent the spectrum of lung diseases caused by inhalation of
respirable particulate matter small enough (typically< 5-µm diameter) to reach the terminal …