Miniaturized liquid chromatography focusing on analytical columns and mass spectrometry: A review

EVS Maciel, AL de Toffoli, E Sobieski, CED Nazário… - Analytica chimica …, 2020 - Elsevier
The technological advances achieved over the last decades boosted the development of
suitable benchtop platforms to work at miniaturized liquid chromatography scale (capillary …

Challenges and advances in the fabrication of monolithic bioseparation materials and their applications in proteomics research

S Ma, Y Li, C Ma, Y Wang, J Ou, M Ye - Advanced Materials, 2019 - Wiley Online Library
High‐performance liquid chromatography integrated with tandem mass spectrometry (HPLC–
MS/MS) has become a powerful technique for proteomics research. Its performance heavily …

Advances and innovations in liquid chromatography stationary phase supports

K Broeckhoven, G Desmet - Analytical Chemistry, 2020 - ACS Publications
The continuous evolution of stationary phase supports over the past decades have allowed
a vast increase the separation performance in liquid chromatography. As in any …

Monolith columns for liquid chromatographic separations of intact proteins: A review of recent advances and applications

KB Lynch, J Ren, MA Beckner, C He, S Liu - Analytica chimica acta, 2019 - Elsevier
In this article we survey 256 references (with an emphasis on the papers published in the
past decade) on monolithic columns for intact protein separation. Protein enrichment and …

Emerging developments in separation techniques and analysis of chiral pharmaceuticals

S Al-Sulaimi, R Kushwah, M Abdullah Alsibani… - Molecules, 2023 - mdpi.com
Chiral separation, the process of isolating enantiomers from a racemic mixture, holds
paramount importance in diverse scientific disciplines. Using chiral separation methods like …

Nano liquid chromatography columns

SR Wilson, C Olsen, E Lundanes - Analyst, 2019 - pubs.rsc.org
Nano liquid chromatography (nanoLC), with columns having an inner diameter (ID) of≤ 100
μm, can provide enhanced sensitivity and enable analysis of limited samples. NanoLC has …

Miniaturization of liquid chromatography coupled to mass spectrometry: 1. Current trends on miniaturized LC columns

K Mejia-Carmona, JS da Silva Burato… - TrAC Trends in …, 2020 - Elsevier
Over the last decade, the use of miniaturized columns in liquid chromatography (LC) has
seen intense growth in a wide range of research areas. This report brings an overview of the …

Advancements in the preparation and application of monolithic silica columns for efficient separation in liquid chromatography

HT Khoo, CH Leow - Talanta, 2021 - Elsevier
Fast and efficient separation remains a big challenge in high performance liquid
chromatography (HPLC). The need for higher efficiency and resolution in separation is …

Recent advances in mesoporous materials for sample preparation in proteomics research

J Yao, N Sun, C Deng - TrAC Trends in Analytical Chemistry, 2018 - Elsevier
Sample preparation is an indispensable part of proteomics research. Owing to their merits
such as large surface area, narrow pore size distribution, adjustable pore size, and …

Preparation of surface protein imprinted thermosensitive polymer monolithic column and its specific adsorption for BSA

J Wang, Y Huyan, Z Yang, H Zhang, A Zhang, X Kou… - Talanta, 2019 - Elsevier
In this work, a novel thermosensitive surface protein imprinted polymer monolithic column
(TsIPMC) was synthesized by combining high internal phase emulsion with 1, 1 …