One-carbon (1C) metabolism comprises a series of interlinking metabolic pathways that
include the methionine and folate cycles that are central to cellular function, providing 1C …

There are numerous theories of aging, a process which still seems inevitable. Aging leads to
cancer and multi-systemic disorders as well as chronic diseases. Decline in age-associated …

Adequate levels of folates are essential for homeostasis of the organism, prevention of
congenital malformations, and the salvage of predisposed disease states. They depend on …

Coronary artery disease (CAD) is a prevalent cardiovascular condition characterized by the
accumulation of plaque within coronary arteries. While distinct features of CAD have been …

Objectives We investigated the relationship between non‐syndromic cleft lip/palate (NSCLP)
and polymorphisms in methylenetetrahydrofolate reductase (MTHFR), methionine synthase …

Homozygosity for the C677T polymorphism in MTHFR (TT genotype) is associated with a 24–
87% increased risk of hypertension. Blood pressure (BP) lowering was previously reported …

Background: Imbalance of homocysteine (Hcy) metabolism links with several pathologies;
nevertheless, it is poorly characterized in pediatric populations. This study investigated the …

Preeclampsia is a multisystemic condition causing severe implications in mothers and
children suffering from proteinuria and gestational hypertension. Globally, there is an …

Family history of hypertension, smoking, diabetes and alcohol consumption and
atherosclerotic plaque were identified as common risk factors in IS. We aimed at …

Corynebacterium glutamicum S9114 is commonly used for industrial glutamate production.
Therefore, a comprehensive understanding of the physiological and metabolic …