Chronic low-grade inflammation in adipose tissue (AT) is a hallmark of obesity and
contributes to various metabolic disorders, such as type 2 diabetes and cardiovascular …

Besides its role as an energy storage organ, adipose tissue can be viewed as a dynamic
and complex endocrine organ, which produces and secretes several adipokines, including …

The breakthrough discoveries of leptin and adiponectin more than two decades ago led to a
widespread recognition of adipose tissue as an endocrine organ. Many more adipose tissue …

Adipose, skeletal, and hepatic muscle tissues are the main endocrine organs that produce
adipokines, myokines, and hepatokines. These biomarkers can be harmful or beneficial to …

Adipose tissue is an immunologically active organ that controls host physiology, partly
through the release of mediators termed adipokines. In obesity, adipocytes and infiltrating …

The global burden of obesity has multiplied owing to its rapidly growing prevalence and
obesity-related morbidity and mortality. In addition to the classic role of depositing extra …

Proper functioning of the body depends on hormonal homeostasis. White adipose tissue is
now known as an endocrine organ due to the secretion of multiple molecules called …

Metabolic syndrome (MetS) is a cluster of risk factors for various metabolic diseases, and it is
characterized by central obesity, dyslipidemia, hypertension, and insulin resistance. The …

The growing burden of obesity and osteoporosis is a major public health concern. Emerging
evidence of the role of adipokines on bone metabolism has led to the discovery of novel …

Gestational diabetes mellitus (GDM) is considered to be one of the most frequent medical
complication observed among pregnant women. The role of adipokines in the pathogenesis …