The development of programmable biomaterials for use in nanofabrication represents a
major advance for the future of biomedicine and diagnostics. Recent advances in structural …

Biological cells routinely reconfigure their shape using dynamic signalling and regulatory
networks that direct self-assembly processes in time and space, through molecular …

Cell-free biosensors are powerful platforms for monitoring human and environmental health.
Here, we expand their capabilities by interfacing them with toehold-mediated strand …

Bottom-up synthetic biology aims to engineer artificial cells capable of responsive behaviors
by using a minimal set of molecular components. An important challenge toward this goal is …

Synthetic biology integrates diverse engineering disciplines to create novel biological
systems for biomedical and technological applications. The substantial growth of the …

Living cells have the ability to control the dynamics of responsive assemblies such as the
cytoskeleton by temporally activating and deactivating inert precursors. While DNA …

We demonstrate here the use of DNA repair enzymes to control the assembly of DNA‐based
structures. To do so, we employed uracil‐DNA glycosylase (UDG) and formamidopyrimidine …

Genomic DNA is compacted via chromatin condensation in mammalian cells, and
transcription of such topologically constrained DNA to messenger RNA is under strict …

Here, we present a cross-linking approach to covalently functionalize and stabilize DNA
origami structures in a one-pot reaction. Our strategy involves adding nucleotide sequences …

Recently, due to the dual roles of DNA and enzyme, DNAzyme has been widely used in the
field of DNA circuit, which has a wide range of applications in bio-engineered system …