Phase‐transfer catalysis has been recognized as a powerful method for establishing
practical protocols for organic synthesis, because it offers several advantages, such as …

Chiral molecules containing asymmetric carbon centers bonded with nitrogen are ubiquitous
in nature and also form important structural fragments in both natural and man-made …

Reactions that utilize addition of active C− H nucleophiles to C X bonds represent some of
the most fundamental carbon− carbon bond-forming processes in organic chemistry. Of …

The development of new asymmetric methodologies that afford different structures in an
enantioselective fashion is one of the most exciting goals for chemists nowadays. In this …

Chiral, metal-free Brønsted bases have been demonstrated capable of catalyzing several
types of C–C and C–X bond-forming reactions with high chemical and stereochemical …

This article reviews the applications of cinchona alkaloids as asymmetric catalysts. In the last
few years, characterized by the resurgence of interest in asymmetric organocatalysis …

An experimental and computational investigation of amido-thiourea promoted imine
hydrocyanation has revealed a new and unexpected mechanism of catalysis. Rather than …

The full details of a catalytic asymmetric syn-selective nitro-Mannich reaction promoted by
heterobimetallic Cu/Sm/dinucleating Schiff base complexes are described, demonstrating …

Oxyanion holes are commonly found in many enzyme structures. They are crucial for the
stabilization of high-energy oxyanion intermediates or transition states through hydrogen …

Over the past three decades, chiral phase-transfer catalysts (PTCs) have emerged as highly
successful organocatalysts in a diverse range of asymmetric reactions. A substantial number …