MicroRNA regulation of bone marrow mesenchymal stem cell chondrogenesis: toward articular cartilage

DJ Vail, RA Somoza, AI Caplan - Tissue Engineering Part A, 2022 - liebertpub.com
The production of a clinically useful engineered cartilage is an outstanding and unmet
clinical need. High-throughput RNA sequencing provides a means of characterizing the …

Knock-Out of the Five Lysyl-Oxidase Family Genes Enables Identification of Lysyl-Oxidase Pro-Enzyme Regulated Genes

T Liburkin-Dan, I Nir-Zvi, H Razon, O Kessler… - International Journal of …, 2022 - mdpi.com
The five lysyl-oxidase genes share similar enzymatic activities and contribute to tumor
progression. We have knocked out the five lysyl-oxidase genes in MDA-MB-231 breast …

[HTML][HTML] Nephron progenitors rhythmically alternate between renewal and differentiation phases that synchronize with kidney branching morphogenesis

SN Davis, SH Grindel, JM Viola, GY Liu, J Liu… - …, 2024 - pmc.ncbi.nlm.nih.gov
The mammalian kidney achieves massive parallelization of function by exponentially
duplicating nephron-forming niches during development. Each niche caps a tip of the …

Nephron progenitors rhythmically alternate between renewal and differentiation in synchrony with kidney branching morphogenesis.

SN Davis, SH Grindel, JM Viola, GY Liu… - Biorxiv: the Preprint …, 2023 - europepmc.org
The mammalian kidney achieves massive parallelization of function by exponentially
duplicating nephron-forming niches during development. Each niche caps a tip of the …

[图书][B] Mapping the Way Toward an Engineered Articular Cartilage: A Complete Transcriptional Characterization of Native and MSC-Derived Cartilage

D Vail - 2021 - search.proquest.com
Injury to articular cartilage is common, often progresses to a degenerative cycle of
dysfunction and inflammation, and can ultimately result in degenerative joint diseases. The …