Quantitative magnetic resonance imaging towards clinical application in multiple sclerosis
Quantitative MRI provides biophysical measures of the microstructural integrity of the CNS,
which can be compared across CNS regions, patients, and centres. In patients with multiple …
which can be compared across CNS regions, patients, and centres. In patients with multiple …
Probing myelin content of the human brain with MRI: A review
Rapid and efficient transmission of electric signals among neurons of vertebrates is ensured
by myelin‐insulating sheaths surrounding axons. Human cognition, sensation, and motor …
by myelin‐insulating sheaths surrounding axons. Human cognition, sensation, and motor …
An atlas for human brain myelin content throughout the adult life span
AV Dvorak, T Swift-LaPointe, IM Vavasour, LE Lee… - Scientific reports, 2021 - nature.com
Myelin water imaging is a quantitative neuroimaging technique that provides the myelin
water fraction (MWF), a metric highly specific to myelin content, and the intra-/extra-cellular …
water fraction (MWF), a metric highly specific to myelin content, and the intra-/extra-cellular …
The CALIPR framework for highly accelerated myelin water imaging with improved precision and sensitivity
Quantitative magnetic resonance imaging (MRI) techniques are powerful tools for the study
of human tissue, but, in practice, their utility has been limited by lengthy acquisition times …
of human tissue, but, in practice, their utility has been limited by lengthy acquisition times …
[HTML][HTML] Myelin water imaging data analysis in less than one minute
Purpose Based on a deep learning neural network (NN) algorithm, a super fast and easy to
implement data analysis method was proposed for myelin water imaging (MWI) to calculate …
implement data analysis method was proposed for myelin water imaging (MWI) to calculate …
Does siponimod exert direct effects in the central nervous system?
M Kipp - Cells, 2020 - mdpi.com
The modulation of the sphingosine 1-phosphate receptor is an approved treatment for
relapsing multiple sclerosis because of its anti-inflammatory effect of retaining lymphocytes …
relapsing multiple sclerosis because of its anti-inflammatory effect of retaining lymphocytes …
Multi‐spin echo T2 relaxation imaging with compressed sensing (METRICS) for rapid myelin water imaging
Purpose Myelin water imaging (MWI) provides a valuable biomarker for myelin, but clinical
application has been restricted by long acquisition times. Accelerating the standard multi …
application has been restricted by long acquisition times. Accelerating the standard multi …
[HTML][HTML] Advanced spinal cord MRI in multiple sclerosis: Current techniques and future directions
Spinal cord magnetic resonance imaging (MRI) has a central role in multiple sclerosis (MS)
clinical practice for diagnosis and disease monitoring. Advanced MRI sequences capable of …
clinical practice for diagnosis and disease monitoring. Advanced MRI sequences capable of …
Harnessing myelin water fraction as an imaging biomarker of human cerebral aging, neurodegenerative diseases, and risk factors influencing myelination: A review
Myelin water fraction (MWF) imaging has emerged as a promising magnetic resonance
imaging (MRI) biomarker for investigating brain function and composition. This …
imaging (MRI) biomarker for investigating brain function and composition. This …
Sensitivity of the inhomogeneous magnetization transfer imaging technique to spinal cord damage in multiple sclerosis
H Rasoanandrianina, S Demortière… - American Journal …, 2020 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The inhomogeneous magnetization transfer technique
has demonstrated high specificity for myelin, and has shown sensitivity to multiple sclerosis …
has demonstrated high specificity for myelin, and has shown sensitivity to multiple sclerosis …