Synchronized proinsulin trafficking reveals delayed Golgi export accompanies β-cell secretory dysfunction in rodent models of hyperglycemia
The pancreatic islet β-cell's preference for release of newly synthesized insulin requires
careful coordination of insulin exocytosis with sufficient insulin granule production to ensure …
careful coordination of insulin exocytosis with sufficient insulin granule production to ensure …
β-cell secretory capacity as an adaptive mechanism during the development of type 2 diabetes
CK Boyer - 2024 - search.proquest.com
Abstract Type 2 diabetes (T2D) impacts millions of Americans and is characterized by three
primary features: persistently high insulin levels, elevated blood sugar levels, and insulin …
primary features: persistently high insulin levels, elevated blood sugar levels, and insulin …
Search for Insulin Secretion Modulators, Novel Functions of WNK Signaling and Intramolecular Signal Transduction in ERK2
MG Grzemska - 2022 - utswmed-ir.tdl.org
In this dissertation, the regulation of insulin secretion from pancreatic beta cells, WNK1
pathway involvement in cell migration, angiogenesis, breast cancer, and other processes, as …
pathway involvement in cell migration, angiogenesis, breast cancer, and other processes, as …
[引用][C] 以内质网应激为靶标治疗1 型糖尿病的药物研究进展
张子洋， 王莉， 陈春麟， 张梦军 - 中国医药导报 - yiyaodaobao.com.cn
1 型糖尿病(T1DM) 是器官特异性的自身免疫病, 目前临床中缺乏T1DM 的根治手段,
内质网应激是早期T1DM 发病的重要病理特征和促进其发生发展的重要因素 …
内质网应激是早期T1DM 发病的重要病理特征和促进其发生发展的重要因素 …