Sleep is implicated in cognitive functioning in young adults. With increasing age, there are
substantial changes to sleep quantity and quality, including changes to slow-wave sleep …

The mechanisms involved in plasticity in the nervous system are thought to support
cognition, and some of these processes are affected during normal ageing. Notably …

We examine similar and differential effects of two senolytic treatments, ABT‐263 and
dasatinib+ quercetin (D+ Q), in preserving cognition, markers of peripheral senescence, and …

The Morris water maze task was originally designed to assess the rat's ability to learn to
navigate to a specific location in a relatively large spatial environment. This article describes …

Aging is associated with specific impairments of learning and memory, some of which are
similar to those caused by hippocampal damage. Studies of the effects of aging on …

Neurogenesis occurs within the adult dentate gyrus of the hippocampal formation and it has
been proposed that the newly born neurons, recruited into the preexistent neuronal circuits …

The noradrenaline (norepinephrine) system exerts profound influences on cognition via
ascending projections to the forebrain, mostly originating from the locus coeruleus. This …

Habituation to a novel environment in rodents is commonly defined as a change in
exploratory or locomotor activity over time (intrasession) or with repeated exposures …

Cognitive alterations occur over the lifespan of every species studied and have been
quantified carefully in humans, other primates and rodents. Correspondingly, changes in …

Abstract Serotonin (5-hydroxytryptamien, 5-HT) has been linked to emotional and
motivational aspects of human behavior, including anxiety, depression, impulsivity, etc …