Non-small cell lung cancer (NSCLC) is characterized by molecular heterogeneity with
diverse immune cell infiltration patterns, which has been linked to therapy sensitivity and …

Deciphering cell-type heterogeneity is crucial for systematically understanding tissue
homeostasis and its dysregulation in diseases. Computational deconvolution is an efficient …

While the association between colorectal cancer (CRC) features and Fusobacterium has
been extensively studied, less is known of other intratumoral bacteria. Here, we leverage …

Transcriptome profiling is a mainstay of translational cancer research and is increasingly
finding its way into precision oncology. While bulk RNA sequencing (RNA-seq) is widely …

Cutaneous leishmaniasis is a localized infection controlled by CD4+ T cells that produce IFN-
γ within lesions. Phagocytic cells recruited to lesions, such as monocytes, are then exposed …

Pediatric brain and spinal cancers are collectively the leading disease-related cause of
death in children; thus, we urgently need curative therapeutic strategies for these tumors. To …

Objective Inclusion body myositis (IBM) has an unclear molecular etiology exhibiting both
characteristic inflammatory T-cell activity and rimmed-vacuolar degeneration of muscle …

Seminoma is the most common type of testicular germ cell tumors (TGCTs) among 15–44
years old men. Seminoma treatments include orchiectomy, platinum-based chemotherapy …

Associated with high morbidity and mortality, lung adenocarcinoma (LUAD) is lacking in
effective prognostic prediction and treatment. As chemotherapy drugs commonly used in …

The tumour immune microenvironment (TIME) in breast cancer is acknowledged with an
increasing role in treatment response and prognosis. With a growing number of immune …