Tendinopathy is a multi-faceted pathology characterized by alterations in tendon
microstructure, cellularity and collagen composition. Challenged by the possibility of …

PIEZO1 and PIEZO2 are mechanosensitive cation channels that are highly expressed in
numerous tissues throughout the body and exhibit diverse, cell-specific functions in multiple …

Tendon injuries heal via a scar-mediated response, and there are no biological approaches
to promote more regenerative healing. Mouse flexor tendons heal through the formation of …

Restoring the normal structure and function of injured tendons is one of the biggest
challenges in orthopedics and sports medicine department. The discovery of tendon-derived …

Peripheral neurons terminate at the surface of tendons partly to relay nociceptive pain
signals; however, the role of peripheral nerves in tendon injury and repair remains unclear …

Apolipoprotein D is a chordate gene early originated in the Lipocalin protein family. Among
other features, regulation of its expression in a wide variety of disease conditions in humans …

The myotendinous junction (MTJ) is a specialized domain of the multinucleated myofibre
that is faced with the challenge of maintaining robust cell–matrix contact with the tendon …

Despite the requirement for Scleraxis-lineage (ScxLin) cells during tendon development, the
function of ScxLin cells during adult tendon repair, post-natal growth, and adult homeostasis …

Tendon is a bradytrophic and hypovascular tissue, hence, healing remains a major
challenge. The molecular key events involved in successful repair have to be unravelled to …

Tendon disorders affect people of all ages, from elite and recreational athletes and workers
to elderly patients. After an acute injury, 3 successive phases are described to achieve …