Biological regulation is what allows an organism to handle the effects of a perturbation,
modulating its own constitutive dynamics in response to particular changes in internal and …

There is frequent confusion about the terms autocatalytic reaction, autocatalytic cycle, and
autocatalytic set. As the use of the same adjective implies, these three systems do indeed …

A rich literature has grown up over the years that bears with autopoiesis, which tends to
assume that it is a model, a theory, a principle, a definition of life, a property, refers to self …

The Gaia hypothesis states that the Earth is an instance of life. However, appraisals of it tend
to focus on the claim that life is a feedback self-regulator that controls Earth's chemistry and …

Reaction network is a promising framework for representing complex systems of diverse and
even interdisciplinary types. In this approach, complex systems appear as self‐maintaining …

We present a novel approach to represent ecological systems using reaction networks, and
show how a particular framework called chemical organization theory (COT) sheds new light …

Cycles are abundant in most kinds of networks, especially in biological ones. Here, we
investigate their role in the evolution of a chemical reaction system from one self-sustaining …

Self-sustaining autocatalytic chemical networks represent a necessary, though not sufficient
condition for the emergence of early living systems. These networks have been formalised …

RAF theory has been established as a useful and formal framework for studying the
emergence and evolution of autocatalytic sets. Here, we present several new and additional …

Disagreement over whether life is inevitable when the conditions can support life remains
unresolved, but calculations show that self-organization can arise naturally from purely …