Patients experiencing mental disorders are at an elevated risk for developing aggressive
behavior. In the past 10 years, the psychopharmacological treatment of aggression has …

Background For psychotic disorders (ie schizophrenia), pharmacotherapy plays a key role in
controlling acute and long-term symptoms. To find the optimal individual dose and dosage …

Previous studies have suggested a disturbance in the cortical serotonergic (5-HT) system in
schizophrenia; however, these studies have been confounded by suicide in the patient …

Three atypical antipsychotics are currently considered to be first-line therapies for
schizophrenia, namely risperidone, olanzapine, and quetiapine. Deciding which one of …

The management of agitation and aggression in psychiatric inpatients is a significant clinical
dilemma. Establishing a clear diagnosis and distinguishing whether aggression is an acute …

OBJECTIVE: Loxapine, a dibenzoxazepine antipsychotic, is closely related to clozapine and
shares clozapine's high affinity for binding to serotonin 5-HT2 and dopamine D4 receptors …

Introduction: Drug development and repurposing are urgently needed for individuals with
autism spectrum disorders (ASD) and psychiatric comorbidity, which often presents as …

The typicality of atypical antipsychotic drugs remains debatable. Preclinical studies and
findings from randomized, controlled and open trials of clozapine, olanzapine, risperidone …

Molecular imaging, the study of receptors, transporters and enzymes, as well as other
cellular processes, has grown in recent years to be one of the most active neuroimaging …

Psychomotor agitation is often associated with aggression. It is important to identify agitation
early and achieve results quickly in order to prevent aggressive behavior. Strategies may …