Adrenal insufficiency can arise from a primary adrenal disorder, secondary to
adrenocorticotropic hormone deficiency, or by suppression of adrenocorticotropic hormone …

Neuroendocrinology of bone is a new area of research based on the evidence that pituitary
hormones may directly modulate bone remodeling and metabolism. Skeletal fragility …

Adrenal insufficiency (AI) is a life-threatening condition requiring life-long glucocorticoid
(GC) substitution therapy, as well as stress adaptation to prevent adrenal crises. The number …

The effects of long-term replacement therapy of adrenal insufficiency (AI) are still a matter of
controversy. In fact, the established glucocorticoid replacement regimens do not completely …

Objective Mortality from primary and secondary adrenal insufficiency (AI; PAI and SAI,
respectively) is 2‐3‐fold higher than in the general population. Mortality relates to …

Context Mortality and infection-related hospital admissions are increased in patients with
primary adrenal insufficiency (PAI). However, the risk of primary care–managed infections in …

Context Glucocorticoid (GC) replacement therapy in patients with adrenal insufficiency (AI) is
life saving. After over 50 years of conventional GC treatment, novel formulations are now …

The adrenal glands are small endocrine glands located on top of each kidney, producing
hormones regulating important functions in our body like metabolism and stress. There are …

Objective This study aimed to characterize the clinical and biochemical features of patients
with primary (PAI) and secondary (SAI) adrenal insufficiency who developed adrenal crises …

Background Patients with adrenal insufficiency (AI) have excess morbidity and mortality
related to infectious disorders. Whether patients with AI have increased morbidity and …