[HTML][HTML] Sleep disorders and Alzheimer's disease pathophysiology: The role of the Glymphatic System. A scoping review

K Astara, A Tsimpolis, K Kalafatakis… - Mechanisms of ageing …, 2024 - Elsevier
Background Alzheimer's disease (AD) is highly intertwined with sleep disturbances
throughout its whole natural history. Sleep consists of a major compound of the functionality …

Individual sleep need is flexible and dynamically related to cognitive function

AM Fjell, KB Walhovd - Nature Human Behaviour, 2024 - nature.com
Given that sleep deprivation studies consistently show that short sleep causes
neurocognitive deficits, the effects of insufficient sleep on brain health and cognition are of …

[HTML][HTML] Matrix metalloproteinase-9 inhibition prevents aquaporin-4 depolarization-mediated glymphatic dysfunction in Parkinson's disease

X Si, S Dai, Y Fang, J Tang, Z Wang, Y Li… - Journal of advanced …, 2024 - Elsevier
Introduction The glymphatic system offers a perivascular pathway for the clearance of
pathological proteins and metabolites to optimize neurological functions. Glymphatic …

Glymphatic system impairment in sleep disruption: diffusion tensor image analysis along the perivascular space (DTI-ALPS)

Y Saito, Y Hayakawa, K Kamagata, J Kikuta… - Japanese Journal of …, 2023 - Springer
Purpose This study aimed to evaluate the relationship between sleep quality as assessed
using the Pittsburgh Sleep Quality Index (PSQI) and the index of diffusivity along the …

Long-wavelength traveling waves of vasomotion modulate the perfusion of cortex

T Broggini, J Duckworth, X Ji, R Liu, X Xia, P Mächler… - Neuron, 2024 - cell.com
Brain arterioles are active, multicellular complexes whose diameters oscillate at∼ 0.1 Hz.
We assess the physiological impact and spatiotemporal dynamics of vaso-oscillations in the …

Effects of sleep on the glymphatic functioning and multimodal human brain network affecting memory in older adults

J Ma, M Chen, GH Liu, M Gao, NH Chen, CH Toh… - Molecular …, 2024 - nature.com
Understanding how sleep affects the glymphatic system and human brain networks is crucial
for elucidating the neurophysiological mechanism underpinning aging-related memory …

Sleep and perivascular spaces

BK Dredla, OH Del Brutto, PR Castillo - Current neurology and …, 2023 - Springer
Abstract Purpose of Review The glymphatic system is hypothesized to act as the brain's
filtration system to remove toxic solutes that accumulate throughout the day. Perivascular …

[HTML][HTML] Effects of sleep on brain perivascular space in a cognitively healthy population

NC Shih, G Barisano, KD Lincoln, WJ Mack… - Sleep Medicine, 2023 - Elsevier
The magnetic resonance imaging (MRI) visible perivascular space (PVS) reportedly clears
amyloid-β and metabolic waste during sleep. Previous studies reported an association …

Integrating the science of epigenetics with existential–humanistic counseling to increase wellness with Black males

I Burt, LA Tosado - The Journal of Humanistic Counseling, 2024 - Wiley Online Library
The recent emphasis on racial unrest and systemic inequality perpetuated by COVID‐19 has
made the counseling profession seek more appropriate methods for clients, especially with …

Glymphatic system dysfunction in restless legs syndrome: evidenced by diffusion tensor imaging along the perivascular space

KM Park, KT Kim, DA Lee, GK Motamedi, YW Cho - Sleep, 2023 - academic.oup.com
Abstract Study Objectives There is growing evidence pointing at glymphatic system
dysfunction in diseases with circadian disruption, such as sleep disorders. Lower diffusivity …