Device-induced hemostatic disorders in mechanically assisted circulation

S Wang, BP Griffith, ZJ Wu - Clinical and Applied …, 2021 - journals.sagepub.com
Mechanically assisted circulation (MAC) sustains the blood circulation in the body of a
patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) or on ventricular …

Stroke and mechanical circulatory support in adults

DJ Bae, JZ Willey, C Ibeh, M Yuzefpolskaya… - Current Cardiology …, 2023 - Springer
Abstract Purpose of the Review Short-term and durable mechanical circulatory support
(MCS) devices represent life-saving interventions for patients with cardiogenic shock and …

Impella 5.5 as a bridge to heart transplantation: Waitlist outcomes in the United States

M Cevasco, M Shin, W Cohen… - Clinical …, 2023 - Wiley Online Library
Abstract Objectives The 2018 United Network for Organ Sharing allocation policy change
has led to a significant increase in the use of mechanical circulatory support devices in …

Surgically implanted Impella device for patients on Impella CP support experiencing refractory hemolysis

IS de Armas, A Bergeron, A Bhardwaj… - ASAIO …, 2022 - journals.lww.com
Abstract The Impella CP (Abiomed Inc., Danvers, MA) is widely used in cardiac
catheterization laboratories for patients presenting with cardiogenic shock, but it is also …

A case series analysis on the clinical experience of Impella 5.5® at a large tertiary care centre

PJ Kennel, H Lumish, Y Kaku, J Fried… - ESC Heart …, 2021 - Wiley Online Library
Aims We aimed to detail the early clinical experience with pVAD 5.5 at a large academic
medical centre. Impella® 5.5 (Abiomed) is a temporary peripherally inserted left ventricular …

Shear-mediated platelet microparticles demonstrate phenotypic heterogeneity as to morphology, receptor distribution, and hemostatic function

Y Roka-Moiia, KR Ammann, S Miller-Gutierrez… - International journal of …, 2023 - mdpi.com
Implantable Cardiovascular Therapeutic Devices (CTD), while lifesaving, impart
supraphysiologic shear stress to platelets, resulting in thrombotic and bleeding …

Preservation of von Willebrand factor activity with the ModulHeart device

G Georges, F Trudeau, J Potvin, F Potus… - Basic to Translational …, 2024 - jacc.org
Summary von Willebrand Factor (VWF) destruction is common with current heart pumps.
This study evaluates VWF activity with ModulHeart, a novel device using 3 micropumps in …

[HTML][HTML] Device‐induced platelet dysfunction in patients after left ventricular assist device implantation

K Klaeske, MT Dieterlen, S Eifert, U Scholz… - Journal of Thrombosis …, 2021 - Elsevier
Background Non‐surgical bleeding (NSB) is a major complication after left ventricular assist
device (LVAD) implantation. It has been reported that non‐physiological shear stress …

Coarse-grained model of whole blood hemolysis and morphological analysis of erythrocyte population under non-physiological shear stress flow environment

Z Xu, C Wang, F He, P Hao, X Zhang - Physics of Fluids, 2023 - pubs.aip.org
Erythrocyte dynamics and hemorheology exist inextricably connection. In order to further
explore the population dynamics of erythrocytes in non-physiological shear stress flow and …

Shear stress promotes remodeling of platelet glycosylation via upregulation of platelet glycosidase activity: one more thing

Y Roka-Moiia, S Lewis, E Cleveland… - Thrombosis and …, 2024 - thieme-connect.com
Background Mechanical circulatory support (MCS) is a mainstay of therapy for advanced
and end-stage heart failure. Accompanied by systemic anticoagulation, contemporary MCS …