Monoclonal antibodies (mAbs) are often selected from antigen-specific single B cells
derived from different hosts, which are notably short-lived in ex vivo culture conditions and …

Over the past three decades, improved immunosuppression has significantly reduced T cell–
mediated acute rejection rates, but long-term graft survival rates have seen only marginal …

We report the development of a novel flow cytometry–based Ig capture assay (ICA) for the
identification and sorting of individual Ab-secreting cells based on their Ag reactivity. The …

Problem The immunophenotype of B cells at the maternal‐fetal interface (decidua) in labor
at term and preterm labor is poorly understood. Method of study Decidual tissues were …

Background Antibodies against citrullinated proteins (ACPA) are common in patients with
rheumatoid arthritis (RA). ACPA can appear before disease onset and target many self …

The purpose of this review is to encourage a new perspective on the question of donor–
recipient compatibility and post‐transplant assessment of graft health based on functional …

Hepatitis C (HCV) is a rapidly mutating RNA virus, with a strong propensity to cause chronic
infection and progressive liver disease. Recent evidence has shown that early appearance …

Selection of single antigen-specific B cells to identify their expressed antibodies is of
considerable interest for evaluating human immune responses. Here, we present a method …

Whether a transplanted allograft is stably accepted, rejected, or achieves immunological
tolerance is dependent on the frequency and function of alloreactive lymphocytes, making …

The complex mechanisms of humoral allorecognitition in transplantation seem to be
progressively better understood with the implementation of novel immune technologies. This …