M Lipovsek, C Bardy, CR Cadwell… - Journal of …, 2021 - Soc Neuroscience
Single-cell transcriptomic approaches are revolutionizing neuroscience. Integrating this wealth of data with morphology and physiology, for the comprehensive study of neuronal …
Simultaneous profiling of multiomic modalities within a single cell is a grand challenge for single-cell biology. While there have been impressive technical innovations demonstrating …
Current biotechnologies can simultaneously measure multiple high-dimensional modalities (eg, RNA, DNA accessibility, and protein) from the same cells. A combination of different …
Multi-modal learning is essential for understanding information in the real world. Jointly learning from multi-modal data enables global integration of both shared and modality …
The advancement of single-cell RNA-sequencing technologies has led to an explosion of cell type definitions across multiple organs and organisms. While standards for data and …
T Athaya, RC Ripan, X Li, H Hu - Briefings in Bioinformatics, 2023 - academic.oup.com
Integrating single-cell multi-omics data is a challenging task that has led to new insights into complex cellular systems. Various computational methods have been proposed to effectively …
N Cohen Kalafut, X Huang, D Wang - Nature Machine Intelligence, 2023 - nature.com
Single-cell multimodal datasets have measured various characteristics of individual cells, enabling a deep understanding of cellular and molecular mechanisms. However …
Paired mapping of single-cell gene expression and electrophysiology is essential to understand gene-to-function relationships in electrogenic tissues. Here, we developed in …
Consistent identification of neurons in different experimental modalities is a key problem in neuroscience. Although methods to perform multimodal measurements in the same set of …