Abstract Background Cancer stem cells (CSCs), which are involved in cancer initiation and
metastasis, could potentially release exosomes that mediate cellular communication by …

Nitric oxide synthase (NOS) plays important roles within the cardiovascular system in
physiological states as well as in pathophysiologic and specific cardiovascular (CV) disease …

Glioma is the most commonly observed primary intracranial tumour and is associated with
massive angiogenesis. Glioma neovascularization provides nutrients for the growth and …

Background Diabetic retinopathy is the most common complication in diabetic patients
relates to high expression of VEGF and microaneurysms. Scutellarin (Scu) turned out to be …

Blood vessel endothelial dysfunction induced by oxidized low-density lipoprotein (ox-LDL)
has been implicated in the pathogenesis of atherosclerosis and vasculopathy. The ox-LDL …

Osteoporosis is a disease of the skeleton that is characterized by the loss of bone mass and
degeneration of bone microstructure, resulting in an increased risk of fracture. Oxidative …

Hyperactivation of the mechanistic target of rapamycin (mTOR) signaling pathway is linked
to more than a dozen neurologic diseases, causing a range of pathologies, including excess …

Background Different strategies have been proposed to target neoangiogenesis in gliomas,
besides those targeting Vascular Endothelial Growth Factor (VEGF). The chemokine …

Objective: Micro-RNA plays a critical role in the pathological process of gliomas. Previous
research showed that the level of miR-155 was significantly increased in many cancers …

Objective To investigate the role and molecular mechanism of membrane-associated
guanylate kinase inverted 3 (MAGI3) in glioma cell proliferation. Methods The expression …