[HTML][HTML] Unfinished story of polyamines: Role of conjugation, transport and light-related regulation in the polyamine metabolism in plants

M Pál, G Szalai, OK Gondor, T Janda - Plant Science, 2021 - Elsevier
Polyamines play a fundamental role in the functioning of all cells. Their regulatory role in
plant development, their function under stress conditions, and their metabolism have been …

Polyamines: Α bioenergetic smart switch for plant protection and development

E Navakoudis, K Kotzabasis - Journal of Plant Physiology, 2022 - Elsevier
The present review highlights the bioenergetic role of polyamines in plant protection and
development and proposes a universal model for describing polyamine-mediated stress …

Subtype‐specific transcription factors affect polyamine metabolism and the tumor microenvironment in breast cancer

Q Song, Y Wang, S Liu - Cancer Innovation, 2025 - Wiley Online Library
Background Polyamines play important roles in cell growth and proliferation. Polyamine
metabolism genes are dysregulated in various tumors. Some polyamine metabolism genes …

Dual Inhibition of Ornithine Decarboxylase and A1 Adenosine Receptor Efficiently Suppresses Breast Tumor Cells

H Ma, Q Li, J Wang, J Pan, Z Su, S Liu - Frontiers in Oncology, 2021 - frontiersin.org
Personized treatment of breast cancer is still a challenge, and more treatment options for
breast cancer are warranted. Combination therapies have been a highly appreciated …

Repurposing clinical drugs as AdoMetDC inhibitors using the SCAR strategy

Y Zhang, Q Zheng, Y Zhou, S Liu - Frontiers in Pharmacology, 2020 - frontiersin.org
With the escalating costs in drug development, discovering new uses of approved drugs, ie,
drug repurposing, has attracted increasing interest. Spermidine and spermine are important …

The rational discovery of multipurpose inhibitors of the ornithine decarboxylase

X Chai, J Zhan, J Pan, M He, B Li, J Wang… - The FASEB …, 2020 - Wiley Online Library
Metabolic reprograming is a hallmark of cancer, and the polyamine metabolic network is
dysregulated in many cancers. Ornithine decarboxylase (ODC) is a rate‐limiting enzyme for …

A systems approach discovers the role and characteristics of seven LysR type transcription factors in Escherichia coli

IA Rodionova, Y Gao, J Monk, Y Hefner, N Wong… - Scientific reports, 2022 - nature.com
Although Escherichia coli K-12 strains represent perhaps the best known model bacteria, we
do not know the identity or functions of all of their transcription factors (TFs). It is now …

Prognostic, oncogenic roles, and pharmacogenomic features of AMD1 in hepatocellular carcinoma

Y Zhou, Y Zhou, J Hu, Y Xiao, Y Zhou, L Yu - Cancer Cell International, 2024 - Springer
Background AMD1 is the gene encoding S-adenosylmethionine decarboxylase 1. How
AMD1 affects the prognosis of hepatocellular carcinoma (HCC) patients is unclear. Methods …

PtrR (YneJ) is a novel E. coli transcription factor regulating the putrescine stress response and glutamate utilization

IA Rodionova, Y Gao, A Sastry, J Monk, N Wong… - bioRxiv, 2020 - biorxiv.org
Although polyamines, such as putrescine (Ptr), induce envelope stress for bacteria, they are
important as nitrogen and carbon sources. Ptr utilization in Escherichia coli involves protein …

[PDF][PDF] Circadian rhythm and body health: A review of the literature.

SS Eftekhar Vaghefi, RM Afshar… - Physiology & …, 2024 - ppj.phypha.ir
Circadian rhythm is a biological clock that regulates various physiological and pathological
processes in the body. It is believed that any disturbance in circadian rhythm leads to …