Diverse inflammatory diseases, infections and malignancies are associated with wasting
syndromes. In many of these conditions, the standards for diagnosis and treatment are …

Depression and fatigue are conditions responsible for heavy global societal burden,
especially in patients already suffering from chronic diseases. These symptoms have been …

In this study, we investigated lipopolysaccharide (LPS)-induced cognitive impairment and
neuroinflammation in C57BL/6J mice by using behavioral tests, immunofluorescence …

Siloed or singular system approach to disease management is common practice,
developing out of traditional medical school education. Textbooks of medicine describe a …

Immune processes have a vital role in CNS homeostasis, resilience and brain reserve. Our
cognitive and social abilities rely on a highly sensitive and fine-tuned equilibrium of immune …

BACKGROUND Contagious pathogens can trigger diverse changes in host social
behaviors, rewiring their social networks and profoundly influencing the extent and pace of …

Neuroimmunology is one of the fastest-growing fields in the life sciences, and for good
reason; it fills the gap between two principal systems of the organism, the nervous system …

To identify the physical effects, behavioral changes, and gene expression profiles of the
phase 1 detoxification-related gene (cyp 1a) and oogenesis-related gene (vtg 1) induced by …

Infections induce a set of pleiotropic responses in animals, including anorexia, adipsia,
lethargy and changes in temperature, collectively termed sickness behaviours. Although …

Central nervous system (CNS) barriers predominantly mediate the immune-privileged status
of the brain, and are also important regulators of neuroimmune communication. It is …