Streptozotocin (STZ) has been extensively used over the last three decades to induce diabetes in various animal species and to help screen for hypoglycemic drugs. STZ induces …
Abstract 'Smart'bandages based on multimodal wearable devices could enable real-time physiological monitoring and active intervention to promote healing of chronic wounds …
K Kolczynska, A Loza-Valdes, I Hawro… - Lipids in health and …, 2020 - Springer
Protein kinase C (PKC) and Protein kinase D (PKD) isoforms can sense diacylglycerol (DAG) generated in the different cellular compartments in various physiological processes …
K Flynn, NN Mahmoud, S Sharifi, LJ Gould… - ACS Pharmacology & …, 2023 - ACS Publications
In this paper, we review and analyze the commonly available wound healing models reported in the literature and discuss their advantages and issues, considering their …
J Wu, Z Jin, H Zheng, LJ Yan - Diabetes, metabolic syndrome and …, 2016 - Taylor & Francis
NAD+ is a fundamental molecule in metabolism and redox signaling. In diabetes and its complications, the balance between NADH and NAD+ can be severely perturbed. On one …
M Yu, D Agarwal, L Korutla, CL May, W Wang… - Nature …, 2020 - nature.com
The intrahepatic milieu is inhospitable to intraportal islet allografts,–, limiting their applicability for the treatment of type 1 diabetes. Although the subcutaneous space …
A King, J Bowe - Biochemical pharmacology, 2016 - Elsevier
Diabetes mellitus is a lifelong, metabolic disease that is characterised by an inability to maintain normal glucose homeostasis. There are several different forms of diabetes …
Y Cheng, L Sibusiso, L Hou, H Jiang, P Chen… - International Journal of …, 2019 - Elsevier
Diabetes is a complicated endocrine and metabolic disorder, which has become an epidemic health issue worldwide. Fucoidan is extensively distributed in the brown algae and …
AMTA Nahdi, A John, H Raza - Oxidative medicine and cellular …, 2017 - Wiley Online Library
Streptozotocin is a pancreatic beta‐cell‐specific cytotoxin and is widely used to induce experimental type 1 diabetes in rodent models. The precise molecular mechanism of STZ …