Fracture healing in the setting of endocrine diseases, aging, and cellular senescence

D Saul, S Khosla - Endocrine reviews, 2022 - academic.oup.com
Abstract More than 2.1 million age-related fractures occur in the United States annually,
resulting in an immense socioeconomic burden. Importantly, the age-related deterioration of …

Macrophages—bone marrow mesenchymal stem cells crosstalk in bone healing

S Fan, X Sun, C Su, Y Xue, X Song… - Frontiers in Cell and …, 2023 - frontiersin.org
Bone healing is associated with many orthopedic conditions, including fractures and
osteonecrosis, arthritis, metabolic bone disease, tumors and periprosthetic particle …

A critical review on the 3D bioprinting in large bone defects regeneration

M Shahrezaie, A Zamanian, M Sahranavard… - Bioprinting, 2024 - Elsevier
Bone injuries are increasing due to the ageing of the population, and the previous methods
of treating bone injuries such as grafts face many limitations, especially in the treatment of …

Establishment of a human 3D in vitro liver-bone model as a potential system for drug toxicity screening

G Chen, Y Xin, MM Hammour, B Braun, S Ehnert… - Archives of …, 2024 - Springer
Drug toxicity is an important cause of chronic liver damage, which in the long term can lead
to impaired bone homeostasis through an imbalance in the liver-bone axis. For instance …

Dual-Mode Release of IL-4 and TCP from a PGA-SF Core–Shell Electrospinning Scaffold for Enhanced Bone Regeneration through Synergistic Immunoregulation …

X Jiang, Y Jian, Y Zhang, J Zhong, Q Li… - … Applied Materials & …, 2024 - ACS Publications
The successful filling of bone defects remains challenging due to the incongruity between
bone graft materials and the dynamic process of bone healing. Developing multifunctional …

[HTML][HTML] Treatment strategies for dental implant removal: A literature review

C Masaki, Y Kondo, K Tomoeda, T Nodai… - … Dental Science Review, 2024 - Elsevier
Dental implants have been widely used with success, but long-term usage sometimes leads
to implant loss. The purpose of this review was to summarize the etiology of early and late …

Nonsteroidal anti-inflammatory drugs in the acute post-operative period are associated with an increased incidence of pseudarthrosis, hardware failure, and revision …

SE Lindsay, T Philipp, WHA Ryu, C Wright, J Yoo - Spine, 2023 - journals.lww.com
Study Design. Retrospective study. Summary of Background Data. Research has shown that
the use of NSAIDs and COX-2 inhibitors increases the risk of pseudoarthrosis following …

NSAID chronotherapy after impacted third molar extraction: a randomized controlled trial

Z Tamimi, M Abusamak, H Al-Waeli… - Oral and Maxillofacial …, 2022 - Springer
Objectives Postoperative pain management impacts patients' quality of life and morbidity.
Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen are widely used for this …

Contrasting experimental rodent aftercare with human clinical treatment for cervical spinal cord injury: Bridging the translational “Valley of Death”

AL Silverstein, KG Lawson, HF Farhadi… - Journal of …, 2023 - liebertpub.com
More than half of all spinal cord injuries (SCIs) occur at the cervical level and often lead to
life-threatening breathing motor dysfunction. The C2 hemisection (C2Hx) and high cervical …

[HTML][HTML] Comparison of Two Synthesis Methods for 3D PLA-Ibuprofen Nanofibrillar Scaffolds

E Mena-Porras, A Contreras-Aleman… - Pharmaceutics, 2025 - mdpi.com
Objectives: This study aimed to synthesize polylactic acid (PLA) nanofibrillar scaffolds
loaded with ibuprofen (IBU) using electrospinning (ES) and air-jet spinning (AJS). The …