Mechanisms of fish macrophage antimicrobial immunity

L Grayfer, B Kerimoglu, A Yaparla… - Frontiers in …, 2018 - frontiersin.org
Overcrowding conditions and temperatures shifts regularly manifest in large-scale infections
of farmed fish, resulting in economic losses for the global aquaculture industries. Increased …

Review of inflammation in fish and value of the zebrafish model

JC Campos‐Sánchez, MÁ Esteban - Journal of Fish Diseases, 2021 - Wiley Online Library
Inflammation is a crucial step in the development of chronic diseases in humans.
Understanding the inflammation environment and its intrinsic mechanisms when it is …

Immune functions of phagocytic blood cells in teleost

W Zhu, J Su - Reviews in Aquaculture, 2022 - Wiley Online Library
Phagocytosis is a fundamental immune function against foreign microorganisms and
abnormal cells, and it is also a bridge between innate and adaptive immunity. Blood as the …

Macrophage-pathogen interactions in infectious diseases: new therapeutic insights from the zebrafish host model

V Torraca, S Masud, HP Spaink… - Disease models & …, 2014 - journals.biologists.com
Studying macrophage biology in the context of a whole living organism provides unique
possibilities to understand the contribution of this extremely dynamic cell subset in the …

Polarization of immune responses in fish: The 'macrophages first'point of view

GF Wiegertjes, AS Wentzel, HP Spaink, PM Elks… - Molecular …, 2016 - Elsevier
In this review, we support taking polarized immune responses in teleost fish from a
'macrophage first'point of view, a hypothesis that reverts the dichotomous T helper (TH) 1 …

Biology of bony fish macrophages

JW Hodgkinson, L Grayfer, M Belosevic - Biology, 2015 - mdpi.com
Macrophages are found across all vertebrate species, reside in virtually all animal tissues,
and play critical roles in host protection and homeostasis. Various mechanisms determine …

Phenotypic modulation of macrophages in response to plaque lipids

S Adamson, N Leitinger - Current opinion in lipidology, 2011 - journals.lww.com
Phenotypic modulation of macrophages in response to plaque l... : Current Opinion in
Lipidology Phenotypic modulation of macrophages in response to plaque lipids : Current …

Evolutionary roots of arginase expression and regulation

JM Dzik - Frontiers in immunology, 2014 - frontiersin.org
Two main types of macrophage functions are known: classical (M1), producing nitric oxide,
NO, and M2, in which arginase activity is primarily expressed. Ornithine, the product of …

Nitric oxide function and nitric oxide synthase evolution in aquatic chordates

A Locascio, G Annona, F Caccavale… - International Journal of …, 2023 - mdpi.com
Nitric oxide (NO) is a key signaling molecule in almost all organisms and is active in a
variety of physiological and pathological processes. Our understanding of the peculiarities …

Innate immune responses of salmonid fish to viral infections

B Collet - Developmental & Comparative Immunology, 2014 - Elsevier
Viruses are the most serious pathogenic threat to the production of the main aquacultured
salmonid species the rainbow trout Oncorhynchus mykiss and the Atlantic salmon Salmo …