Recent Approaches for the Topical Treatment of Psoriasis Using Nanoparticles

K Bodnár, P Fehér, Z Ujhelyi, I Bácskay, L Józsa - Pharmaceutics, 2024 - mdpi.com
Psoriasis (PSO) is a chronic autoimmune skin condition characterized by the rapid and
excessive growth of skin cells, which leads to the formation of thick, red, and scaly patches …

Optimization of Potential Nanoemulgels for Boosting Transdermal Glimepiride Delivery and Upgrading Its Anti-Diabetic Activity

MH Abdallah, AS Abu Lila, HM El-Nahas, TM Ibrahim - Gels, 2023 - mdpi.com
Transdermal drug delivery has been widely adopted as a plausible alternative to the oral
route of administration, especially for drugs with poor systemic bioavailability. The objective …

Enhancing oral bioavailability of dasatinib via supersaturable SNEDDS: Investigation of precipitation inhibition and IVIVC through in-vitro lipolysis-permeation model

D Mageshvaran, S Yadav, V Yadav, K Kuche… - International Journal of …, 2025 - Elsevier
Dasatinib (DASA), a potent second-generation multitarget kinase inhibitor marketed as
Sprycel®(Tablet), is limited by poor oral bioavailability (14–24%) and dose-related …

Harnessing the potential of fatty Acid-Surfactant-Based micellar gel for enhanced topical delivery of Apremilast in psoriasis treatment

A Sontakke, S Dighe, R Sharma, V Yadav… - International Journal of …, 2024 - Elsevier
Apremilast (APR) is a potent anti-psoriatic agent that inhibits the phosphodiesterase 4
enzyme. Due to the poor oral bioavailability and associated systemic side effects the clinical …

Ionic liquid-based Ionogel: A novel strategy to improve dermal delivery and in vivo efficacy of etodolac in rheumatoid arthritis management

S Bhamble, S Dighe, O Katari, V Yadav… - Journal of Molecular …, 2024 - Elsevier
The systemic delivery of Etodolac (ETO) often triggers side effects eg, myocardial problems,
bleeding, etc. thus impeding its clinical usage. Also, ETO exhibits unfavourable …