Three decades of ultrasound contrast agents: a review of the past, present and future improvements

P Frinking, T Segers, Y Luan, F Tranquart - Ultrasound in medicine & …, 2020 - Elsevier
Initial reports from the 1960s describing the observations of ultrasound contrast
enhancement by tiny gaseous bubbles during echocardiographic examinations prompted …

Acoustic behavior of microbubbles and implications for drug delivery

K Kooiman, HJ Vos, M Versluis, N De Jong - Advanced drug delivery …, 2014 - Elsevier
Ultrasound contrast agents are valuable in diagnostic ultrasound imaging, and they
increasingly show potential for drug delivery. This review focuses on the acoustic behavior …

Nonlinear shell behavior of phospholipid-coated microbubbles

M Overvelde, V Garbin, J Sijl, B Dollet… - Ultrasound in medicine …, 2010 - Elsevier
The influence of the stabilizing phospholipid-coating on the nonlinear dynamics of
ultrasound contrast agent microbubbles is investigated. We record the radial dynamics of …

A review of phospholipid encapsulated ultrasound contrast agent microbubble physics

B Helfield - Ultrasound in medicine & biology, 2019 - Elsevier
Ultrasound contrast agent microbubbles have expanded the utility of biomedical ultrasound
from anatomic imaging to the assessment of microvascular blood flow characteristics and …

Buckling of lipidic ultrasound contrast agents under quasi-static load

G Chabouh, B van Elburg… - … of the Royal …, 2023 - royalsocietypublishing.org
Collapse of lipidic ultrasound contrast agents under high-frequency compressive load has
been historically interpreted by the vanishing of surface tension. By contrast, buckling of …

[HTML][HTML] Sonobactericide: an emerging treatment strategy for bacterial infections

KR Lattwein, H Shekhar, JJP Kouijzer… - Ultrasound in medicine …, 2020 - Elsevier
Ultrasound has been developed as both a diagnostic tool and a potent promoter of
beneficial bio-effects for the treatment of chronic bacterial infections. Bacterial infections …

Physical principles of microbubbles for ultrasound imaging and therapy

E Stride - Cerebrovascular Diseases, 2009 - karger.com
Microbubble ultrasound contrast agents have been in clinical use for more than two
decades, during which time their range of applications has increased to encompass …

Spherical oscillations of encapsulated microbubbles: Effect of shell compressibility and anisotropy

G Chabouh, B Dollet, C Quilliet… - The Journal of the …, 2021 - pubs.aip.org
We introduce a model that describes spherical oscillations of encapsulated microbubbles in
an unbounded surrounding fluid. A Rayleigh–Plesset-like equation is derived by coupling …

Nonlinear resonance behavior and linear shell estimates for Definity™ and MicroMarker™ assessed with acoustic microbubble spectroscopy

BL Helfield, DE Goertz - The Journal of the Acoustical Society of …, 2013 - pubs.aip.org
There is a growing interest in microbubble based ultrasound contrast imaging applications
in the 5–15 MHz range. In this study, individual microbubbles were insonified at low …

Targeted ultrasound contrast agents for ultrasound molecular imaging and therapy

T van Rooij, V Daeichin, I Skachkov… - International journal …, 2015 - Taylor & Francis
Ultrasound contrast agents (UCAs) are used routinely in the clinic to enhance contrast in
ultrasonography. More recently, UCAs have been functionalised by conjugating ligands to …