Three perspectives on the prediction of chemical effects in ecosystems
A Schneeweiss, NPD Juvigny‐Khenafou… - Global Change …, 2023 - Wiley Online Library
The increasing production, use and emission of synthetic chemicals into the environment
represents a major driver of global change. The large number of synthetic chemicals, limited …
represents a major driver of global change. The large number of synthetic chemicals, limited …
Using CRISPR/Cas9 genome modification to understand the genetic basis of insecticide resistance: Drosophila and beyond
Chemical insecticides are a major tool for the control of many of the world's most damaging
arthropod pests. However, their intensive application is often associated with the emergence …
arthropod pests. However, their intensive application is often associated with the emergence …
[HTML][HTML] Diversity and evolution of the P450 family in arthropods
The P450 family (CYP genes) of arthropods encodes diverse enzymes involved in the
metabolism of foreign compounds and in essential endocrine or ecophysiological functions …
metabolism of foreign compounds and in essential endocrine or ecophysiological functions …
Low doses of the neonicotinoid insecticide imidacloprid induce ROS triggering neurological and metabolic impairments in Drosophila
Declining insect population sizes are provoking grave concern around the world as insects
play essential roles in food production and ecosystems. Environmental contamination by …
play essential roles in food production and ecosystems. Environmental contamination by …
Discovery of multitarget inhibitors against insect chitinolytic enzymes via machine learning-based virtual screening
Multitarget inhibitors of insect chitinolytic enzymes are promising sources of green
insecticides. Machine learning (ML) is an emerging virtual screening method that can …
insecticides. Machine learning (ML) is an emerging virtual screening method that can …
'What I cannot create, I do not understand': functionally validated synergism of metabolic and target site insecticide resistance
GR Samantsidis, R Panteleri… - … of the Royal …, 2020 - royalsocietypublishing.org
The putative synergistic action of target-site mutations and enhanced detoxification in
pyrethroid resistance in insects has been hypothesized as a major evolutionary mechanism …
pyrethroid resistance in insects has been hypothesized as a major evolutionary mechanism …
Drosophila melanogaster as a powerful tool for studying insect toxicology
JG Scott, N Buchon - Pesticide Biochemistry and Physiology, 2019 - Elsevier
Insecticides are valuable and widely used tools for the control of pest insects. Despite the
use of synthetic insecticides for> 50 years, we continue to have a limited understanding of …
use of synthetic insecticides for> 50 years, we continue to have a limited understanding of …
The role of ABC transporters in arthropod pesticide toxicity and resistance
Highlights•ABCC2-and ABCC3-based Cry1 resistance was extended to several Lepidoptera
species.•ABCG modulates cuticle thickness in Culex pipiens and contributes to deltamethrin …
species.•ABCG modulates cuticle thickness in Culex pipiens and contributes to deltamethrin …
Describing the role of Drosophila melanogaster ABC transporters in insecticide biology using CRISPR-Cas9 knockouts
S Denecke, R Fusetto, P Batterham - Insect biochemistry and molecular …, 2017 - Elsevier
ABC transporters have a well-established role in drug resistance, effluxing xenobiotics from
cells and tissues within the organism. More recently, research has been dedicated to …
cells and tissues within the organism. More recently, research has been dedicated to …
Partitioning the roles of CYP6G1 and gut microbes in the metabolism of the insecticide imidacloprid in Drosophila melanogaster
Resistance to insecticides through enhanced metabolism is a worldwide problem. The
Cyp6g1 gene of the vinegar fly, Drosophila melanogaster, is a paradigm for the study of …
Cyp6g1 gene of the vinegar fly, Drosophila melanogaster, is a paradigm for the study of …