Fluid shear stress sensing by the endothelial layer

E Roux, P Bougaran, P Dufourcq… - Frontiers in physiology, 2020 - frontiersin.org
Blood flow produces mechanical frictional forces, parallel to the blood flow exerted on the
endothelial wall of the vessel, the so-called wall shear stress (WSS). WSS sensing is …

Applications of phase-contrast flow and velocity imaging in cardiovascular MRI

PD Gatehouse, J Keegan, LA Crowe, S Masood… - European …, 2005 - Springer
A review of cardiovascular clinical and research applications of MRI phase-contrast velocity
imaging, also known as velocity mapping or flow imaging. Phase-contrast basic principles …

Metabolic signatures of exercise in human plasma

GD Lewis, L Farrell, MJ Wood, M Martinovic… - Science translational …, 2010 - science.org
Exercise provides numerous salutary effects, but our understanding of how these occur is
limited. To gain a clearer picture of exercise-induced metabolic responses, we have …

A global multiscale mathematical model for the human circulation with emphasis on the venous system

LO Müller, EF Toro - International journal for numerical …, 2014 - Wiley Online Library
We present a global, closed‐loop, multiscale mathematical model for the human circulation
including the arterial system, the venous system, the heart, the pulmonary circulation and the …

Nonlinear power loss during exercise in single-ventricle patients after the Fontan: insights from computational fluid dynamics

KK Whitehead, K Pekkan, HD Kitajima, SM Paridon… - Circulation, 2007 - Am Heart Assoc
Background—We previously demonstrated that power loss (PL) through the total
cavopulmonary connection (TCPC) in single-ventricle patients undergoing Fontan can be …

Effects of exercise and respiration on hemodynamic efficiency in CFD simulations of the total cavopulmonary connection

AL Marsden, IE Vignon-Clementel, FP Chan… - Annals of biomedical …, 2007 - Springer
Congenital heart defects with a single functional ventricle, such as hypoplastic left heart
syndrome and tricuspid atresia, require a staged surgical approach to separate the systemic …

Evaluating medical device and material thrombosis under flow: current and emerging technologies

JK Hong, L Gao, J Singh, T Goh, AM Ruhoff… - Biomaterials …, 2020 - pubs.rsc.org
Although blood-contacting medical devices are used widely, blood clot formation
(thrombosis) leads to device failure and potentially catastrophic adverse thrombotic events …

Effects of non-Newtonian viscosity on arterial and venous flow and transport

S Lynch, N Nama, CA Figueroa - Scientific Reports, 2022 - nature.com
It is well known that blood exhibits non-Newtonian viscosity, but it is generally modeled as a
Newtonian fluid. However, in situations of low shear rate, the validity of the Newtonian …

Investigation of pulsatile flowfield in healthy thoracic aorta models

CY Wen, AS Yang, LY Tseng, JW Chai - Annals of biomedical engineering, 2010 - Springer
Cardiovascular disease is the primary cause of morbidity and mortality in the western world.
Complex hemodynamics plays a critical role in the development of aortic dissection and …

An anatomically detailed arterial-venous network model. Cerebral and coronary circulation

LO Müller, SM Watanabe, EF Toro, RA Feijóo… - Frontiers in …, 2023 - frontiersin.org
In recent years, several works have addressed the problem of modeling blood flow
phenomena in veins, as a response to increasing interest in modeling pathological …