Role of the intestinal microbiota in contributing to weight disorders and associated comorbidities

M Van Hul, AM Neyrinck, A Everard… - Clinical microbiology …, 2024 - journals.asm.org
The gut microbiota is a major factor contributing to the regulation of energy homeostasis and
has been linked to both excessive body weight and accumulation of fat mass (ie, overweight …

[HTML][HTML] Metabolome analysis for investigating host-gut microbiota interactions

MX Chen, SY Wang, CH Kuo, IL Tsai - Journal of the Formosan Medical …, 2019 - Elsevier
Dysbiosis of the gut microbiome is associated with host health conditions. Many diseases
have shown to have correlations with imbalanced microbiota, including obesity …

Distinct composition and metabolic functions of human gut microbiota are associated with cachexia in lung cancer patients

Y Ni, Z Lohinai, Y Heshiki, B Dome, J Moldvay… - The ISME …, 2021 - academic.oup.com
Cachexia is associated with decreased survival in cancer patients and has a prevalence of
up to 80%. The etiology of cachexia is poorly understood, and limited treatment options …

Energy metabolism in cachexia

M Rohm, A Zeigerer, J Machado, S Herzig - EMBO reports, 2019 - embopress.org
Cachexia is a wasting disorder that accompanies many chronic diseases including cancer
and results from an imbalance of energy requirements and energy uptake. In cancer …

Bile acid metabolism dysregulation associates with cancer cachexia: roles of liver and gut microbiome

L Feng, W Zhang, Q Shen, C Miao… - Journal of cachexia …, 2021 - Wiley Online Library
Background Cancer cachexia is a multifactorial metabolic syndrome in which bile acid (BA)
metabolism might be involved. The aim of the present study was to clarify the contribution of …

Targeting gut microbiota in cancer cachexia: towards new treatment options

C Panebianco, A Villani, A Potenza, E Favaro… - International journal of …, 2023 - mdpi.com
Cancer cachexia is a complex multifactorial syndrome whose hallmarks are weight loss due
to the wasting of muscle tissue with or without the loss of adipose tissue, anorexia, systemic …

Cancer predictive studies

I Amelio, R Bertolo, P Bove, E Candi, M Chiocchi… - Biology direct, 2020 - Springer
The identification of individual or clusters of predictive genetic alterations might help in
defining the outcome of cancer treatment, allowing for the stratification of patients into …

Novel targeted therapies for cancer cachexia

JM Argilés, FJ López-Soriano, B Stemmler… - Biochemical …, 2017 - portlandpress.com
Anorexia and metabolic alterations are the main components of the cachectic syndrome.
Glucose intolerance, fat depletion, muscle protein catabolism and other alterations are …

Neuroblastoma is associated with alterations in gut microbiome composition subsequent to maternal microbial seeding

M Valles-Colomer, P Manghi, F Cumbo, G Masetti… - …, 2024 - thelancet.com
Background Neuroblastoma is the most frequent extracranial solid tumour in children,
accounting for∼ 15% of deaths due to cancer in childhood. The most common clinical …

Cachexia, a systemic disease beyond muscle atrophy

E Wyart, LB Bindels, E Mina, A Menga… - International journal of …, 2020 - mdpi.com
Cachexia is a complication of dismal prognosis, which often represents the last step of
several chronic diseases. For this reason, the comprehension of the molecular drivers of …