Gut microbiota in colorectal cancer: biological role and therapeutic opportunities

H Pandey, DWT Tang, SH Wong, D Lal - Cancers, 2023 - mdpi.com
Simple Summary Colorectal cancer (CRC) is the second-leading cause of cancer-related
deaths worldwide. In this review article, we examine the role of gut microbiota in the …

Colorectal cancer and gut microbiota studies in China

Z Wang, W Dan, N Zhang, J Fang, Y Yang - Gut Microbes, 2023 - Taylor & Francis
Colorectal cancer (CRC) is the third most common malignant tumor worldwide. The
incidence and mortality rates of CRC have been increasing in China, possibly due to …

[HTML][HTML] The role of microbiota in gastrointestinal cancer and cancer treatment: chance or curse?

A Smet, J Kupcinskas, A Link, GL Hold… - Cellular and Molecular …, 2022 - Elsevier
The gastrointestinal (GI) tract is home to a complex and dynamic community of
microorganisms, comprising bacteria, archaea, viruses, yeast, and fungi. It is widely …

Deep insights into the gut microbial community of extreme longevity in south Chinese centenarians by ultra-deep metagenomics and large-scale culturomics

C Li, Z Luan, Y Zhao, J Chen, Y Yang… - npj Biofilms and …, 2022 - nature.com
The gut microbes play important roles in human longevity and the gut microbiota profile of
centenarians shows some unique features from young adults. Nowadays, most microbial …

Intestinal microbiota in colorectal adenoma-carcinoma sequence

H Hua, Y Sun, X He, Y Chen, L Teng, C Lu - Frontiers in Medicine, 2022 - frontiersin.org
Background Most colorectal cancer (CRC) cases are sporadic and develop along the
adenoma-carcinoma sequence. Intestinal microbial dysbiosis is involved in the development …

[HTML][HTML] Inflammation, Gut Microbiota, and Metabolomic Shifts in Colorectal Cancer: Insights from Human and Mouse Models

C Yang, Wusigale, L You, X Li, LY Kwok… - International Journal of …, 2024 - mdpi.com
Colorectal cancer (CRC) arises from aberrant mutations in colorectal cells, frequently linked
to chronic inflammation. This study integrated human gut metagenome analysis with an …

The role of gut microbiota in gastrointestinal tract cancers

M Grochowska, K Perlejewski, T Laskus… - Archivum Immunologiae …, 2022 - Springer
Disturbances in gastrointestinal (GI) microbiota could play a significant role in the
development of GI cancers, but the underlying mechanisms remain largely unclear. While …

Gut microbial and associated metabolite markers for colorectal cancer diagnosis

AA Alhhazmi, RM Alhamawi, RM Almisned… - Microorganisms, 2023 - mdpi.com
Globally, colorectal cancer (CRC) is the second most common cause of mortality worldwide.
Considerable evidence indicates that dysbiosis of the gut microbial community and its …

Endogenous Coriobacteriaceae enriched by a high-fat diet promotes colorectal tumorigenesis through the CPT1A-ERK axis

Q Tang, H Huang, H Xu, H Xia, C Zhang… - npj Biofilms and …, 2024 - nature.com
A high-fat diet (HFD) may be linked to an increased colorectal cancer (CRC) risk. Stem cell
proliferation and adipokine release under inflammatory and obese conditions are the main …

Urogenital microbiota-driven virulence factor genes associated with recurrent urinary tract infection

L Jiang, H Wang, L Luo, X Pang, T Liu, L Sun… - Frontiers in …, 2024 - frontiersin.org
Urinary tract infections (UTIs) are a common health issue affecting individuals worldwide.
Recurrent urinary tract infections (rUTI) pose a significant clinical challenge, with limited …