Gold nanoparticles and gold nanorods in the landscape of cancer therapy

P Kesharwani, R Ma, L Sang, M Fatima, A Sheikh… - Molecular cancer, 2023 - Springer
Cancer is a grievous disease whose treatment requires a more efficient, non-invasive
therapy, associated with minimal side effects. Gold nanoparticles possessing greatly …

Nano-drug delivery systems based on natural products

Y Lv, W Li, W Liao, H Jiang, Y Liu, J Cao… - International Journal …, 2024 - Taylor & Francis
Natural products have proven to have significant curative effects and are increasingly
considered as potential candidates for clinical prevention, diagnosis, and treatment …

Targeting the central nervous system: From synthetic nanoparticles to extracellular vesicles—Focus on Alzheimer's and Parkinson's disease

S Hernando, E Santos‐Vizcaíno… - Wiley …, 2023 - Wiley Online Library
Neurodegenerative diseases (NDs) such as Alzheimer's disease (AD) and Parkinson's
disease (PD) are an accelerating global health problem as life expectancy rises worldwide …

MicroRNA-targeting nanomedicines for the treatment of intervertebral disc degeneration

HH Genedy, P Humbert, B Laoulaou, B Le Moal… - Advanced Drug Delivery …, 2024 - Elsevier
Low back pain stands as a pervasive global health concern, afflicting almost 80% of adults
at some point in their lives with nearly 40% attributable to intervertebral disc degeneration …

Machine learning-guided high throughput nanoparticle design

A Ortiz-Perez, D van Tilborg, R van der Meel… - Digital …, 2024 - pubs.rsc.org
Designing nanoparticles with desired properties is a challenging endeavor, due to the large
combinatorial space and complex structure-function relationships. High throughput …

Nanocarriers of antigen proteins for vaccine delivery

LL Chaves, D Dourado, IB Prunache… - International Journal of …, 2024 - Elsevier
Nanoformulations in vaccinology provide antigen stability and enhanced immunogenicity, in
addition to providing targeted delivery and controlled release. In the last years, much …

Mechanisms and Barriers in Nanomedicine: Progress in the Field and Future Directions

T Anchordoquy, N Artzi, IV Balyasnikova, Y Barenholz… - ACS …, 2024 - ACS Publications
In recent years, steady progress has been made in synthesizing and characterizing
engineered nanoparticles, resulting in several approved drugs and multiple promising …

Multi‐ligand functionalized blood‐to‐tumor sequential targeting strategies in the field of glioblastoma nanomedicine

C Martins, B Sarmento - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
Glioblastoma (GBM) is an unmet clinical need characterized by a standard of care (SOC) 5‐
year survival rate of only 5%, and a treatment mostly palliative. Significant hurdles in GBM …

Clinical and Preclinical Methods of Heat-Stabilization of Human Vaccines

GL Williamson, EM Bachelder… - Molecular …, 2024 - ACS Publications
Vaccines have historically faced challenges regarding stability, especially in regions lacking
a robust cold chain infrastructure. This review delves into established and emergent …

Schiff-Base Cross-Linked Poly (2-oxazoline) Micelle Drug Conjugates Possess Antiferroptosis Activity in Numerous In Vitro Cell Models

JP Morrow, ZAI Mazrad, NM Warne, S Ayton… - …, 2024 - ACS Publications
A great deal of nanocarriers have been applied to induce ferroptosis in cancer research, yet
there are limited examples of nanocarrier formulations to rescue ferroptosis, which can be …