Autophagy is a highly conserved lysosomal degradation pathway active at basal levels in all
cells. However, under stress conditions, such as a lack of nutrients or trophic factors, it works …

Fibroblast growth factor (FGF) belongs to a large family of growth factors. FGFs use
paracrine or endocrine signaling to mediate a myriad of biological and pathophysiological …

The endothelial cells play a crucial role in the progression of angiogenesis, which causes
cell re-modulation, proliferation, adhesion, migration, invasion and survival. Angiogenic …

To elucidate the structural determinants governing specificity in fibroblast growth factor
(FGF) signaling, we have determined the crystal structures of FGF1 and FGF2 complexed …

Fibroblast growth factors (FGFs) are cell-signaling proteins with diverse functions in cell
development, repair, and metabolism. The human FGF family consists of 22 structurally …

The Drosophila sugarless and sulfateless genes encode enzymes required for the
biosynthesis of heparan sulfate glycosaminoglycans. Biochemical studies have shown that …

Keratinocyte growth factor (KGF) is a paracrine-acting, epithelial mitogen produced by cells
of mesenchymal origin. It is a member of the fibroblast growth factor (FGF) family, and acts …

A method for the quantitative estimation of instability with respect to deamidation of the
asparaginyl (Asn) residues in proteins is described. The procedure involves the observation …

Introduction Dental pulp regeneration is a part of regenerative endodontics, which includes
isolation, propagation, and re-transplantation of stem cells inside the prepared root canal …

Deciphering the structural requirements and mechanisms for internalization of cell‐
penetrating peptides (CPPs) is required to improve their delivery efficiency. Herein, a unique …