Opioidergic tuning of social attachment: reciprocal relationship between social deprivation and opioid abuse

JA Galiza Soares, SN Sutley-Koury… - Frontiers in …, 2025 - frontiersin.org
Individuals misusing opioids often report heightened feelings of loneliness and decreased
ability to maintain social connections. This disruption in social functioning further promotes …

[HTML][HTML] Paraventricular Thalamus Neuronal Ensembles Encode Early-life Adversity and Mediate the Consequent Sex-dependent Disruptions of Adult Reward …

CL Kooiker, MT Birnie, A Floriou-Servou, Q Ding… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Early-life adversity increases risk for mental illnesses including depression and substance
use disorders, disorders characterized by dysregulated reward behaviors. However, the …