Connexins are ubiquitous channel forming proteins that assemble as plasma membrane
hemichannels and as intercellular gap junction channels that directly connect cells. In the …

Gap junctions are essential to the function of multicellular animals, which require a high
degree of coordination between cells. In vertebrates, gap junctions comprise connexins and …

Connexins are a family of transmembrane proteins that play a key role in cardiac physiology.
Gap junctional channels put into contact the cytoplasms of connected cardiomyocytes …

Gap junctions consist of arrays of intercellular channels composed of integral membrane
proteins called connexin in vertebrates. Gap junction channels regulate the passage of ions …

Intercellular communication (IC) is mediated by gap junctions (GJs) and hemichannels,
which consist of proteins. This has been particularly well documented for the connexin (Cx) …

Connexin-assembled gap junctions (GJs) and hemichannels coordinate intercellular
signaling processes. Although the regulation of connexins in GJs has been well …

Gap junctional channels are a class of membrane channels composed of transmembrane
channel-forming integral membrane proteins termed connexins, innexins or pannexins that …

The importance of electrical and molecular signaling through connexin (Cx) channels is now
widely recognized. The transfer of ions and other small molecules between adjacent cells is …

About a decade ago, the molecular determinants controlling the opening and closing of
Cx43 gap junction channels have been identified. Advanced biophysical approaches …

The coordination of tissue function is mediated by gap junctions (GJs) that enable direct cell–
cell transfer of metabolic and electric signals. GJs are formed by connexins of which Cx43 is …