Background: Variants in the SCN5A gene, that encodes the cardiac sodium channel, Nav1.
5, are associated with a highly arrhythmogenic form of dilated cardiomyopathy (DCM). Our …

In the past 20 years, genetic variants in SCN5A encoding the cardiac voltage-gated sodium
channel Nav1. 5 have been linked to a range of inherited cardiac arrhythmias: variants …

Abstract The Nexilin F‐Actin Binding Protein (Nexilin) encoded by NEXN is a cardiac Z‐disc
protein important for cardiac function and development in humans, zebrafish, and mice …

Pathogenic heterozygous NEXN variants are associated with progressive dilated
cardiomyopathy (DCM) usually presenting around 50 years of age. We describe an …

Cardiac disorders exhibit considerable heterogeneity, and understanding their genetic
foundations is crucial for their diagnosis and treatment. Recent genetic analyses involving a …

Background Dilated cardiomyopathy (DCM) is an etiologically heterogeneous group of
diseases of the myocardium. With the rapid evolution in laboratory investigations, genetic …

Sudden cardiac death (SCD) is an unexpected cardiac death that is instantaneous or occurs
within a short period of time after onset of symptoms, in a person in a stable state of health …

参仙升脉口服液对病态窦房结综合征小鼠ROS表达的影响和对HCN4离子通道的调控作用 首页
期刊简介 期刊介绍 影响因子 获奖情况 收录情况 编辑部简介 编委会 征稿征订 征稿简则 征订说明 …

Abstract Hereditary cardiomyopathies (CMPs), including Arrhythmogenic Right Ventricular
Cardiomyopathy (ARVC), Dilated Cardiomyopathy (DCM), and Hypertrophic …

Left ventricle apical hypoplasia (LVAH) is a rare congenital anomaly characterized by a
smaller left ventricle (LV) and a surrounding right ventricle (RV). Only few cases have been …