Background Somatostatin and its derivatives are sometimes used for emergency treatment
of bleeding oesophageal varices in patients with cirrhosis of the liver. Objectives To study …

Portal hypertension is one of the main consequences of cirrhosis. It results from a
combination of increased intrahepatic vascular resistance and increased blood flow through …

Endoscopic therapy, involving either injection sclerosis or band ligation, is considered the
intervention of first choice for acute variceal bleeding (AVB). Pharmacologic agents have …

Background Vasoactive medications such as vasopressin, somatostatin and their analogues
(terlipressin, vapreotide and octreotide) are commonly used for the treatment of acute …

Clin Mol Hepatol Volume_26 Number_2 April 2020 https://doi. org/10.3350/cmh. 2019.0010
n clinical practice. Therefore, these revised guidelines for the treatment of varices and HE …

Background & Aims: Studies of octreotide have not demonstrated a consistent benefit in
efficacy or safety compared with conventional therapies. This study statistically pooled …

BACKGROUND & AIMS:: Emergency sclerotherapy is used as a first-line therapy for variceal
bleeding in cirrhosis, although pharmacologic treatment stops bleeding in most patients. We …

OBJECTIVES: Data are scarce on the head-to-head efficacy of terlipressin and octreotide as
an adjuvant therapy to endoscopic management of variceal bleed. The aim of this study was …

Somatostatin (SST) is a 14–amino acid peptide first isolated 30 years ago from the
hypothalamus as a growth hormone–inhibitory substance. 1 Since then, SST has been …

Background Emergency sclerotherapy is widely used as a first line therapy for variceal
bleeding in cirrhosis, although pharmacological treatment may stop bleeding in the majority …