Lactate (La−) has long been at the center of controversy in research, clinical, and athletic
settings. Since its discovery in 1780, La− has often been erroneously viewed as simply a …

The aim of this review was to examine the mechanisms by which physical activity and
inactivity modify muscle fatigue. It is well known that acute or chronic increases in physical …

Muscle physiologists often describe fatigue simply as a decline of muscle force and infer this
causes an athlete to slow down. In contrast, exercise scientists describe fatigue during sport …

Repeated sprint ability (RSA) is a critical success factor for intermittent sport performance.
Repeated sprint training has been shown to improve RSA, we hypothesised that hypoxia …

This review integrates from the single muscle fibre to exercising human the current
understanding of the role of skeletal muscle for whole-body potassium (K+) regulation, and …

Introduction Non-local muscle fatigue (NLMF) is characterized by muscle performance
impairments in a contralateral or remote non-exercised muscle (s) following a fatiguing …

Mechanisms underlying fatigue development and limitations for performance during intense
exercise have been intensively studied during the past couple of decades. Fatigue …

Purpose We recently reported that oral ketone ester (KE) intake before and during the initial
30 min of a 3 h 15 min simulated cycling race (RACE) transiently decreased blood pH and …

The present study examined muscle adaptations and alterations in work capacity in
endurance-trained runners as a result of a reduced amount of training combined with speed …

Perturbations in K+ have long been considered a key factor in skeletal muscle fatigue.
However, the exercise-induced changes in K+ intra-to-extracellular gradient is by itself …