Next to plants, bacteria account for most of the biomass on Earth. They are found
everywhere, although certain species thrive only in specific ecological niches. These …

Escherichia coli still serves as a beloved workhorse for the production of many
biopharmaceuticals as it fulfills essential criteria, such as having fast doubling times …

Nicotinamide mononucleotide (NMN) subsists in all living organisms and has drawn
tremendous attention as a nutraceutical and pharmaceutical product for several diseases …

Human catalase cDNA was cloned into a pEX-C-His vector. Purified recombinant catalase
was immobilized on nanoparticles. Gold and silver nanoparticles were synthesized in a …

Once a therapeutic protein has been produced by a chosen production system, the product
must be separated and recovered from the host system. Cell harvest and recovery serve this …

Process analytical technology is gaining interest in the biopharmaceutical industry as a
means to enable consistency in processing and thereby in product quality via process …

Background: Granulocyte colony-stimulating factor (G-CSF) expressed in engineered
Escherichia coli (E. coli) as a recombinant protein is utilized as an adjunct to chemotherapy …

Almost two decades since biosimilars arrived, we still await their broader adoption, as
anticipated. The roadblocks to this adoption include the high amortized cost of goods due to …

The isolation of the target protein from inclusion bodies (IBs) is a preliminary step to increase
protein titer and to maintain its biological activity. In the present study, the effects of various …

Background: Human granulocyte colony-stimulating factor (hG-CSF) can serve as valuable
biopharmaceutical for research and treatment of the human blood cancer. Transplastomic …