Lysine 101 in the CRAC Motif in Transmembrane Helix 2 Confers Cholesterol-Induced Thermal Stability to the Serotonin1A Receptor

P Sarkar, A Bhat, A Chattopadhyay - The Journal of Membrane Biology, 2022 - Springer
G protein-coupled receptors (GPCRs) constitute the largest class of membrane proteins that
transduce signals across the plasma membrane and orchestrate a multitude of physiological …

Structural Stringency and Optimal Nature of Cholesterol Requirement in the Function of the Serotonin1A Receptor

P Sarkar, M Jafurulla, S Bhowmick… - The Journal of …, 2020 - Springer
The role of membrane cholesterol in modulating G protein-coupled receptor (GPCR)
structure and function has emerged as a powerful theme in contemporary biology. In this …

[图书][B] Application of Molecular Simulations and Machine Learning Methods to Study Biological and Metallic Interfaces in Aqueous Environment

M Aghaaminiha - 2021 - search.proquest.com
Molecular dynamics (MD) simulation is a computational methodology to probe molecular-
level details of physical systems. In MD, the motion of molecules is simulated and from the …

[图书][B] Engineering Plasma Membrane Lipids to Alter Cellular Behavior and Cell-Cell Interactions

A Vahedi - 2021 - search.proquest.com
The plasma membrane of a mammalian cell is an asymmetric bilayer of phospholipids and
cholesterol. The cells invest considerable amount of energy to conserve this feature as the …