There is evidence that diet and nutrition are modifiable risk factors for several cancers, but
associations may be flawed due to inherent biases. Nutritional epidemiology studies have …

Objectives To summarise the evidence and evaluate the validity of the associations between
type 2 diabetes and the risk of developing or dying from cancer. Design An umbrella review …

Objective To evaluate the strength and validity of the evidence for the association between
adiposity and risk of developing or dying from cancer. Design Umbrella review of systematic …

Background Numerous studies have identified potential risk factors and biomarkers for
autism spectrum disorder. We aimed to study the strength and validity of the suggested …

The methods and results of health research are documented in study protocols, full study
reports (detailing all analyses), journal reports, and participant-level datasets. However …

Objective To provide an overview of the breadth and validity of claimed associations
between physical activity and risk of developing or dying from cancer. Design Umbrella …

This is a confession building on a conversation with David Sackett in 2004 when I shared
with him some personal adventures in evidence-based medicine (EBM), the movement that …

Objective Bradford Hill's viewpoints were used to conduct a weight-of-the-evidence
assessment of the association between Parkinson's disease (PD) and rural living, farming …

Objectives Model specification—what adjusting variables are analytically modeled—may
influence results of observational associations. We present a standardized approach to …

There is a strong need for science-based risk assessment that utilizes known data from
diverse sources to arrive at accurate assessments of human health risk. Such assessments …