Surfactant protein D (SP-D) is a multimeric collectin that is involved in innate immune
defense and expressed in pulmonary, as well as non-pulmonary, epithelia. SP-D exerts …

Chronic obstructive pulmonary disease (COPD) is a common chronic inflammatory disease
with high morbidity and mortality rates worldwide. Cytokines, which are the main regulators …

Surfactant proteins (SP) are involved in surfactant function and innate immunity in the
human lung. Both lung function and innate immunity are altered in CF, and altered SP levels …

The alveolar epithelium is covered by a non-cellular layer consisting of an aqueous
hypophase topped by pulmonary surfactant, a lipo-protein mixture with surface-active …

Background COPD is one of the leading causes of morbidity and mortality in both high-and
low-income countries and a major public health burden worldwide. While cigarette smoking …

Abstract The interleukin-1 (IL-1) gene polymorphisms have been implicated in chronic
obstructive pulmonary disease (COPD) risk, but results are controversial. We aimed to …

Abstract Background & Aims The toll‐like receptor‐interferon (TLR–IFN) signalling pathway
plays a crucial role in HBV infection. Human leucocyte antigen (HLA) polymorphisms are …

Abstract Background ALOX5, IL6R and SFTPD are all immune related genes that may be
involved in the development of lung cancer. We sought to explore the effect of …

Interleukins are cytokines involved in systemic inflammation and immune system regulation.
Many studies have investigated the association between common genetic variations in …

Surfactant protein A (SP-A) and D (SP-D) are hydrophilic collagenous C-type lectins, which
were originally discovered in the lungs associated with surfactant phospholipids. It was later …