Latest advances in cryogel technology for biomedical applications

A Memic, T Colombani, LJ Eggermont… - Advanced …, 2019 - Wiley Online Library
There exists a technological need for advanced materials with improved properties for
emerging biomedical applications. Recent developments in macroporous materials have …

PVA-based hydrogels for tissue engineering: A review

A Kumar, SS Han - International journal of polymeric materials and …, 2017 - Taylor & Francis
ABSTRACT Poly (vinyl alcohol)(PVA) is a hydrophilic polymer with excellent biocompatibility
and has been applied in various biomedical areas due to its favorable properties. PVA …

A comprehensive review of cryogels and their roles in tissue engineering applications

KR Hixon, T Lu, SA Sell - Acta biomaterialia, 2017 - Elsevier
The extracellular matrix is fundamental in providing an appropriate environment for cell
interaction and signaling to occur. Replicating such a matrix is advantageous in the support …

Insight into silk-based biomaterials: from physicochemical attributes to recent biomedical applications

G Janani, M Kumar, D Chouhan, JC Moses… - ACS Applied Bio …, 2019 - ACS Publications
Silk, a natural biopolymer, has been used clinically as suture material over thousands of
years and has received much impetus for a plethora of biomedical applications in the last …

Design and assessment of biodegradable macroporous cryogels as advanced tissue engineering and drug carrying materials

IN Savina, M Zoughaib, AA Yergeshov - Gels, 2021 - mdpi.com
Cryogels obtained by the cryotropic gelation process are macroporous hydrogels with a well-
developed system of interconnected pores and shape memory. There have been significant …

Current strategies for treatment of intervertebral disc degeneration: substitution and regeneration possibilities

S van Uden, J Silva-Correia, JM Oliveira… - Biomaterials …, 2017 - spj.science.org
Background Intervertebral disc degeneration has an annual worldwide socioeconomic
impact masked as low back pain of over 70 billion euros. This disease has a high …

[HTML][HTML] Characterization of biomaterials intended for use in the nucleus pulposus of degenerated intervertebral discs

TC Schmitz, E Salzer, JF Crispim, GT Fabra… - Acta biomaterialia, 2020 - Elsevier
Biomaterials for regeneration of the intervertebral disc must meet complex requirements
conforming to biological, mechanical and clinical demands. Currently no consensus on their …

Silk fibroin scaffolds for common cartilage injuries: possibilities for future clinical applications

M Farokhi, F Mottaghitalab, Y Fatahi, MR Saeb… - European Polymer …, 2019 - Elsevier
Regenerating chondral and osteochondral injuries is a main challenge in orthopedics.
Some therapeutic strategies such as joint preservation operations, non-operative …

Multiscale regulation of the intervertebral disc: achievements in experimental, in silico, and regenerative research

L Baumgartner, K Wuertz-Kozak, CL Le Maitre… - International Journal of …, 2021 - mdpi.com
Intervertebral disc (IVD) degeneration is a major risk factor of low back pain. It is defined by a
progressive loss of the IVD structure and functionality, leading to severe impairments with …

Development and evaluation of naproxen-loaded sericin/alginate beads for delayed and extended drug release using different covalent crosslinking agents

ED Freitas, VMS Freitas, PCP Rosa… - Materials Science and …, 2021 - Elsevier
Different polymer matrix compositions based on sericin and alginate blend (using or not the
covalent crosslinking agents dibasic sodium phosphate, polyvinyl alcohol and polyethylene …