The restoration of light response with complex spatiotemporal features in retinal
degenerative diseases towards retinal prosthesis has proven to be a considerable …

Spinal cord injury (SCI) is associated with currently irreversible consequences in several
functional components of the central nervous system. Despite the severity of injury, there …

The vertebrate spinal cord is organized across three developmental axes, anterior‐posterior
(AP), dorsal‐ventral (DV), and medial‐lateral (ML). Patterning of these axes is regulated by …

Neural stem cells in the postnatal telencephalic ventricular-subventricular zone (V-SVZ)
generate new interneurons, which migrate tangentially through the rostral migratory stream …

The spinal cord emerges from a niche of neuromesodermal progenitors (NMPs) formed and
maintained by WNT/fibroblast growth factor (FGF) signals at the posterior end of the embryo …

Cellular heterogeneity within embryonic and adult tissues is involved in multiple biological
and pathological processes. Here, we present a simple epigenomic strategy that allows the …

Background The spinal cord is a crucial part of the vertebrate CNS, controlling movements
and receiving and processing sensory information from the trunk and limbs. However, there …

During development of the CNS, stem and progenitor cell proliferation, cell fate designation,
and patterning decisions are tightly regulated by interdependent networks of key …

Embryonic organoids are emerging as powerful models for studying early mammalian
development. For example, stem cell-derived 'gastruloids' form elongating structures …

Over the past two decades, Pax proteins have received a lot of attention from researchers
working on the generation and assembly of neural circuits during vertebrate development …