Dry eye disease (DED) is one of the major ophthalmological healthcare challenges worldwide. DED is a multifactorial disease characterized by a loss of homeostasis of the tear …
L Sebbag, RA Allbaugh, RF Wehrman… - Journal of Ocular …, 2019 - liebertpub.com
Purpose: The study establishes normative data of tear volume (TV) and tear turnover rate (TTR) in healthy dogs and cats, 2 species commonly used for translational research in …
AE Bradley, LM Wancket, M Rinke… - Journal of toxicologic …, 2021 - jstage.jst.go.jp
The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions Project (www. toxpath. org/inhand. asp) is a joint initiative of the Societies of …
L Sebbag, JP Mochel - Medicinal Research Reviews, 2020 - Wiley Online Library
Preclinical animal studies provide valuable opportunities to better understand human diseases and contribute to major advances in medicine. This review provides a …
Ocular surface disorders, such as dry eye disease, ocular rosacea, and allergic conjunctivitis, are a heterogeneous group of diseases that require an interdisciplinary …
F Corsi, K Arteaga, F Corsi, M Masi, A Cattaneo… - BMC Veterinary …, 2022 - Springer
Background One of the contributing factors to ocular surface health is a stable precorneal tear film. Considering the increasing interest in rabbits as pets and the limited literature …
LN Wei, CH Wu, CT Lin, IH Liu - BMC Veterinary Research, 2022 - Springer
Background Canine keratoconjunctivitis sicca (KCS) is predominantly an immune-mediated disease. Current therapy of canine KCS is mainly by immunosuppressant, but the …
D Lee, Q Lu, SD Sommerfeld, A Chan, NG Menon… - Acta Biomaterialia, 2017 - Elsevier
Hyaluronic acid (HA) solutions effectively lubricate the ocular surface and are used for the relief of dry eye related symptoms. However, HA undergoes rapid clearance due to limited …
Since the seminal work of Wichterle in 1965 describing the first soft contact lenses and their potential for ocular drug delivery, the field has yet to realize his vision. Maintaining all lens …