Structure-function relationship of tear film lipid layer: A contemporary perspective

GA Georgiev, P Eftimov, N Yokoi - Experimental eye research, 2017 - Elsevier
Tear film lipid layer (TFLL) stabilizes the air/tear surface of the human eye. Meibomian gland
dysfunction (MGD) resulting in quantitative and qualitative modifications of TFLL major (> …

Experimental models, induction protocols, and measured parameters in dry eye disease: focusing on practical implications for experimental research

MM Rahman, DH Kim, CK Park, YH Kim - International Journal of …, 2021 - mdpi.com
Dry eye disease (DED) is one of the major ophthalmological healthcare challenges
worldwide. DED is a multifactorial disease characterized by a loss of homeostasis of the tear …

Fluorophotometric assessment of tear volume and turnover rate in healthy dogs and cats

L Sebbag, RA Allbaugh, RF Wehrman… - Journal of Ocular …, 2019 - liebertpub.com
Purpose: The study establishes normative data of tear volume (TV) and tear turnover rate
(TTR) in healthy dogs and cats, 2 species commonly used for translational research in …

International Harmonization of Nomenclature and Diagnostic Criteria (INHAND): nonproliferative and proliferative lesions of the rabbit

AE Bradley, LM Wancket, M Rinke… - Journal of toxicologic …, 2021 - jstage.jst.go.jp
The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for
Lesions Project (www. toxpath. org/inhand. asp) is a joint initiative of the Societies of …

An eye on the dog as the scientist's best friend for translational research in ophthalmology: focus on the ocular surface

L Sebbag, JP Mochel - Medicinal Research Reviews, 2020 - Wiley Online Library
Preclinical animal studies provide valuable opportunities to better understand human
diseases and contribute to major advances in medicine. This review provides a …

Interfacial phenomena and the ocular surface

B Yañez-Soto, MJ Mannis, IR Schwab, JY Li… - The ocular …, 2014 - Elsevier
Ocular surface disorders, such as dry eye disease, ocular rosacea, and allergic
conjunctivitis, are a heterogeneous group of diseases that require an interdisciplinary …

Clinical parameters obtained during tear film examination in domestic rabbits

F Corsi, K Arteaga, F Corsi, M Masi, A Cattaneo… - BMC Veterinary …, 2022 - Springer
Background One of the contributing factors to ocular surface health is a stable precorneal
tear film. Considering the increasing interest in rabbits as pets and the limited literature …

Topical applications of allogeneic adipose-derived mesenchymal stem cells ameliorate the canine keratoconjunctivitis sicca

LN Wei, CH Wu, CT Lin, IH Liu - BMC Veterinary Research, 2022 - Springer
Background Canine keratoconjunctivitis sicca (KCS) is predominantly an immune-mediated
disease. Current therapy of canine KCS is mainly by immunosuppressant, but the …

Targeted delivery of hyaluronic acid to the ocular surface by a polymer-peptide conjugate system for dry eye disease

D Lee, Q Lu, SD Sommerfeld, A Chan, NG Menon… - Acta Biomaterialia, 2017 - Elsevier
Hyaluronic acid (HA) solutions effectively lubricate the ocular surface and are used for the
relief of dry eye related symptoms. However, HA undergoes rapid clearance due to limited …

One week sustained In vivo therapeutic release and safety of novel extended‐wear silicone hydrogel contact lenses

SA DiPasquale, LD Wuchte, RJ Mosley… - Advanced …, 2022 - Wiley Online Library
Since the seminal work of Wichterle in 1965 describing the first soft contact lenses and their
potential for ocular drug delivery, the field has yet to realize his vision. Maintaining all lens …